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Detail of "2022-85-7"

  • CAS Number:
  • 2022-85-7
  • Name:

  • Fluorocytosine

  • Molecular Structure:
  • Formula:
  • C4H4FN3O
  • Molecular Weight:
  • 129.11
  • Synonyms:
  • 5-Flurocytosine;4-amino-5-fluoro-3H-pyrimidin-2-one;Flucytosinum [INN-Latin];Ro 2-9915;Fluorcytosine;Flucytosin;Ancobon (TN);4-Amino-5-fluoro-2-pyrimidinol;Flucitosina [DCIT];5-Fluorocystosine;4-Amino-5-fluoro-2(1H)-pyrimidinone;Ancotyl;6-Amino-2-oxo-5-fluoropyrimidine;2-Hydroxy-4-amino-5-fluoropyrimidine;Flucytosine;Flucytosine (JP14/USP);5-FC;5FC;Alcobon;Cytosine, 5-fluoro- (6CI,7CI,8CI);5-Fluorocytosin;2(1H)-Pyrimidinone, 4-amino-5-fluoro- (8CI)(9CI);Ancotil;Ancobon;Cytosine, 5-fluoro-;
  • EINECS:
  • 217-968-7
  • Density:
  • 1.73 g/cm3
  • Melting Point:
  • 298-300 °C (dec.)(lit.)
  • Solubility:
  • 1.5g/100mL (25 °C) in water
  • Appearance:
  • white crystalline solid
  • Hazard Symbols:
  • HarmfulXn, ToxicT, IrritantXi
  • Risk Codes:
  • 40-36/37/38
  • Safety:
  • 22-24/25-45-36/37-36/37/39-27-26 Details
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CAS No.2022-85-7 FluorocytosineCompetitive Product

Fluorocytosine 【CAS NO.】：2022-85-7 【MF】： C4H4FN3O 【MW】： 129.09

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Fluorocytosine CAS 2022-85-7 MF： C4H4FN3O MW： 129.09

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5-Fluorocytosine

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Product No BBTF-002 Product name 5-Fluorocytosine Chemical name 2-Hydroxy-4-amino-5-fluoropyrimidine; 4-Amino-5-fluoro-2(1H)-pyrimidinone; Molecular formula C4H4FN3O Molecular weight 129.09 Application Capecitabine intermediates The high and reliable quality of our pr

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5-fluoro cytosine

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Name 5-Fluorocytosine CAS No. 2022-85-7 Molecular form C4H4FN3O Molecular weight 129.09 Quality standard BP2002 USPXXVIII CP2005 Packing 25kg/drum,cardboard drum,lined with polyethylene plastic bag Use Antifungal drug

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Reference

Effect of 24 antimicrobial drugs on polymorphonuclear leukocyte adherence
Effect of 24 antimicrobial drugs on polymorphonuclear leukocyte adherence. Li, Si Ying; Seow, W. K.; Thong, Y. H. (Kolling Inst. Med. Res., R. North Shore Hosp., Sydney 4101, Australia). Int. Arch. Allergy Appl. Immunol., 76(2), 151-5 (English) 1985. CODEN: IAAAAM. ISSN: 0020-5915. DOCUMENT TYPE: Journal CA Section: 1 (Pharmacology) The adherence of human neutrophils to nylon fiber microcolumns was markedly resistant to antimicrobial agents; no effect was obsd. with penicillin G [61-33-6], nafcillin [147-52-4], cephalothin [153-61-7], vancomycin [1404-90-6], bacitracin [1405-87-4], tetracycline [60-54-8], minocycline [10118-90-8], doxycycline [564-25-0], chloramphenicol [56-75-7], erythromycin [114-07-8], lincomycin [154-21-2], neomycin [1404-04-2], streptomycin [57-92-1], acetylspiramycin [24916-51-6], 5-fluorocytosine [2022-85-7], sulfisoxazole [127-69-5], tinidazole [19387-91-8], and primaquine [90-34-6]. Only 2 compds. enhanced adherence (oxytetracycline [79-57-2] and rifampicin [13292-46-1]) and only 4 suppressed adherence (colistin [1066-17-7], polymyxin B [1404-26-8], quinine [130-95-0], and chloroquine [54-05-7]) and then only at high concns.
The polyene macrolide antibiotics and 5-fluorocytosine: molecular actions and interactions
The polyene macrolide antibiotics and 5-fluorocytosine: molecular actions and interactions. Kerridge, D.; Whelan, W. L. (Dep. Biochem., Cambridge CB2 1QW, UK). Symp. Br. Mycol. Soc., Volume Date 1983, 9(Mode Action Antifungal Agents), 343-75 (English) 1984. CODEN: BMYSD2. ISSN: 0275-0287. DOCUMENT TYPE: Journal; General Review CA Section: 1 (Pharmacology) Section cross-reference(s): 10 A review with ~150 refs. on the treatment of fungal infections with polyene macrolide antibiotics and 5-fluorocytosine [2022-85-7], including mol. mechanisms, the interactions of the drugs, and the mechanism by which fungi become resistant to the drugs.
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