Welcome to LookChem.com Sign In|Join Free
  • or
Home > Products >  > 

Sitaxsentan

Related Products

Hot Products

Name

Sitaxsentan

EINECS N/A
CAS No. 184036-34-8 Density 1.558 g/cm3
PSA 144.35000 LogP 5.11500
Solubility N/A Melting Point 42-45°
Formula C18H15ClN2O6S2 Boiling Point 663.9 °C at 760 mmHg
Molecular Weight 454.912 Flash Point 355.3 °C
Transport Information N/A Appearance N/A
Safety Risk Codes N/A
Molecular Structure Molecular Structure of 184036-34-8 (N- (4- chloro- 3- methyl- oxazol- 5- yl)- 2- [2- (6- methylbenzo[1,3]dioxol- 5- yl)acetyl]- thiophene- 3- sulfonamide) Hazard Symbols N/A
Synonyms

3-Thiophenesulfonamide,N-(4-chloro-3-methyl-5-isoxazolyl)-2-[(6-methyl-1,3-benzodioxol-5-yl)acetyl]-(9CI);IPI 1040;N-(4-Chloro-3-methyl-5-isoxazolyl)-2-[(2-methyl-4,5-methylenedioxyphenyl)acetyl]thiophene-3-sulfonamide;N-(4-Chloro-3-methyl-5-isoxazolyl)-2-[[3,4-(methylenedioxy)-6-methylphenyl]acetyl]-3-thiophenesulfonamide;Sitax;Sitaxentan;Sitaxsentan;TBC 11251;3-Thiophenesulfonamide, N-(4-chloro-3-methyl-5-isoxazolyl)-2-((6-methyl-1,3-benzodioxol-5-yl)acetyl)-;N-(4-Chloro-3-methyl-5-isoxazolyl)-2-((2-methyl-4,5-methylenedioxyphenyl)acetyl)thiophene-3-sulfonamide;

Article Data 15

Sitaxsentan Specification

The 3-Thiophenesulfonamide,N-(4-chloro-3-methyl-5-isoxazolyl)-2-[2-(6-methyl-1,3-benzodioxol-5-yl)acetyl]-, with the CAS registry number 184036-34-8, has the systematic name of N-(4-chloro-3-methyl-1,2-oxazol-5-yl)-2-[(6-methyl-1,3-benzodioxol-5-yl)acetyl]thiophene-3-sulfonamide. And the molecular formula of this chemical is C18H15ClN2O6S2. It is also known as Sitaxentan, and it is a medication for the treatment of pulmonary arterial hypertension (PAH). What's more, it is an Endothelin A receptor antagonist.

The physical properties of 3-Thiophenesulfonamide,N-(4-chloro-3-methyl-5-isoxazolyl)-2-[2-(6-methyl-1,3-benzodioxol-5-yl)acetyl]- are as following: (1)ACD/LogP: 2.77; (2)# of Rule of 5 Violations: 0 ; (3)#H bond acceptors: 8; (4)#H bond donors: 1; (5)#Freely Rotating Bonds: 5; (6)Polar Surface Area: 135.56 Å2; (7)Index of Refraction: 1.65; (8)Molar Refractivity: 106.57 cm3; (9)Molar Volume: 291.9 cm3; (10)Polarizability: 42.24×10-24cm3; (11)Surface Tension: 68.4 dyne/cm; (12)Density: 1.558 g/cm3; (13)Flash Point: 355.3 °C; (14)Enthalpy of Vaporization: 97.64 kJ/mol; (15)Boiling Point: 663.9 °C at 760 mmHg; (16)Vapour Pressure: 1.71E-17 mmHg at 25°C.

You can still convert the following datas into molecular structure:
(1)SMILES: O=C(c1sccc1S(=O)(=O)Nc2onc(c2Cl)C)Cc4cc3OCOc3cc4C
(2)InChI: InChI=1/C18H15ClN2O6S2/c1-9-5-13-14(26-8-25-13)7-11(9)6-12(22)17-15(3-4-28-17)29(23,24)21-18-16(19)10(2)20-27-18/h3-5,7,21H,6,8H2,1-2H3
(3)InChIKey: PHWXUGHIIBDVKD-UHFFFAOYAJ

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 184036-34-8