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Teflubenzuron

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Name

Teflubenzuron

EINECS N/A
CAS No. 83121-18-0 Density 1.646 g/cm3
PSA 58.20000 LogP 4.97560
Solubility 66 g/L in dimethyl sulfoxide, 20 g/L in cyclohexanone, 10 g/L in acetone, 1.4 g/L in ethanol, 850 mg/L in toluene, 50 mg/L in hexane, 0.02 mg/L in water at the temperature of 20 - 23 °C Melting Point 221-224°
Formula C14H6Cl2F4N2O2 Boiling Point N/A
Molecular Weight 381.113 Flash Point N/A
Transport Information UN 3077 Appearance white crystal
Safety Risk Codes N/A
Molecular Structure Molecular Structure of 83121-18-0 (Teflubenzuron) Hazard Symbols N/A
Synonyms

AC291898;CME 134;CME 13406;Calicide;HOE 522;MK 139;Nomolt;Nomolt agro;OMS 3009;Tefluron;N-[(3,5-Dichloro-2,4-difluorophenyl)carbamoyl]-2,6-difluorobenzamide;1-(3,5-Dichloro-2,4-difluorophenyl)-3-(2,6-difluorobenzoyl)urea;

Article Data 7

Teflubenzuron Specification

The Teflubenzuron, with the CAS registry number 83121-18-0, is also known as 1-(3,5-Dichloro-2,4-difluorophenyl)-3-(2,6-difluorobenzoyl)urea. It belongs to the product categories of Alpha sort; Growth regulators Pesticides & Metabolites; Insecticides; Pesticides; Q-ZAlphabetic; TA - TE. This chemical's molecular formula is C14H6Cl2F4N2O2 and molecular weight is 381.11. What's more, its systematic name is N-[(3,5-Dichloro-2,4-difluorophenyl)carbamoyl]-2,6-difluorobenzamide. Its classification codes are: (1)Insecticide; (2)Agricultural Chemical. This chemical is a kind of insect growth regulators. It is effective against development of house fly larvae. It should be sealed and stored in a cool, ventilated and dry place.

Physical properties of Teflubenzuron are: (1)ACD/LogP: 5.017; (2)# of Rule of 5 Violations: 1; (3)ACD/LogD (pH 5.5): 5.01; (4)ACD/LogD (pH 7.4): 4.58; (5)ACD/BCF (pH 5.5): 3743.06; (6)ACD/BCF (pH 7.4): 1399.99; (7)ACD/KOC (pH 5.5): 12491.05; (8)ACD/KOC (pH 7.4): 4671.94; (9)#H bond acceptors: 4; (10)#H bond donors: 2; (11)#Freely Rotating Bonds: 2; (12)Polar Surface Area: 58.2 Å2; (13)Index of Refraction: 1.597; (14)Molar Refractivity: 78.851 cm3; (15)Molar Volume: 231.487 cm3; (16)Polarizability: 31.259×10-24cm3; (17)Surface Tension: 51.44 dyne/cm; (18)Density: 1.646 g/cm3.

Preparation: this chemical can be prepared by 2,6-Difluorobenzamide and 2, 4-difluoro-3, 5-dichlorophenylisocyanate. It can also be prepared by 2,6-Difluorobenzoyl isocyanate and 2,4-difluoro-3, 5-dichloroaniline at the room temperature. This reaction will need solvent toluene with the reaction time of 15 hours.

You can still convert the following datas into molecular structure:
(1)SMILES: Clc1cc(c(F)c(Cl)c1F)NC(=O)NC(=O)c2c(F)cccc2F
(2)Std. InChI: InChI=1S/C14H6Cl2F4N2O2/c15-5-4-8(12(20)10(16)11(5)19)21-14(24)22-13(23)9-6(17)2-1-3-7(9)18/h1-4H,(H2,21,22,23,24)
(3)Std. InChIKey: CJDWRQLODFKPEL-UHFFFAOYSA-N

The toxicity data is as follows:

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 oral > 5gm/kg (5000mg/kg)   Nippon Noyaku Gakkaishi. Journal of the Pesticide Science Society of Japan. Vol. 18, Pg. S15, 1993.
rat LC50 inhalation > 5038mg/m3/4H (5038mg/m3)   Nippon Noyaku Gakkaishi. Journal of the Pesticide Science Society of Japan. Vol. 18, Pg. S15, 1993.
rat LD50 oral > 5gm/kg (5000mg/kg)   Pesticide Manual. Vol. 9, Pg. 790, 1991.
rat LD50 skin > 2gm/kg (2000mg/kg)   Pesticide Manual. Vol. 9, Pg. 790, 1991.

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