The antifungal activity of quinazoline and benzoxazinone derivatives can be evaluated through in vitro and in vivo assays. Researchers typically test the compounds against a range of fungal strains, including yeast and molds, to determine their effectiveness in inhibiting fungal growth. MIC (Minimum Inhibitory Concentration) assays are commonly used to measure the lowest concentration of the compound that effectively inhibits fungal growth. Structure-activity relationship (SAR) studies are often conducted to understand which structural features of these derivatives contribute to their antifungal properties.
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3,5-dibromo-2-isobutyrylaminobenzoyl-hydrazine
4-fluoro-benzoic acid 4-allyl-2-methoxy-phenyl ester
9-(tert-butyldiphenylsilyloxy)methyl-5-hydroxy-2-methyl-8,11-dihydro-4H-oxepino[2,3-h]chromen-4-one
methyl 17,17-dimethyl-3-(tosyloxyimino)octadec-4-ynoate
5-Hexenoic acid, 6-(3,4-dimethoxyphenyl)-3-methyl-4-oxo-, methyl ester, (5E)-
4-[4-(4-{4-[(2R,5R)-5-(2,4-Difluoro-phenyl)-5-[1,2,4]triazol-1-ylmethyl-tetrahydro-furan-2-ylmethoxy]-phenyl}-piperazin-1-yl)-phenyl]-2-(2-methoxy-ethoxymethyl)-2,4-dihydro-[1,2,4]triazol-3-one
1-(1H-1,2,4-triazol-1-yl)-2-(2,4-difluorophenyl)-3-{N-[(1-(2-fluorobenzyl)-1H-1,2,3-triazol-4-yl)methyl]amino}-2-propanol
1-(4-Bromo-phenyl)-2-(4,5-dihydro-3H-pyrrol-2-ylamino)-ethanone; hydrochloride
2-(4-bromophenyl)-1-(1H-imidazol-1-yl)-3-(1H-indol-1-yl)propan-2-ol
3-(4-hydroxy-3-methoxyphenyl)-1-(2-hydroxyphenyl)-2-propen-1-one
5-(4-Fluorophenyl)-2,3,6,7,8,9-hexahydro-5H-thiazolo[2,3-b]quinazoline-3,6-dione
N-(2-(4-hydroxy-3-methoxyphenyl)-4-oxo-1,4-dihydroquinazolin-3(2H)-yl)nicotinamide
1-(3-nitrophenyl)-2-phenyl-4-(4'-methoxybenzylidene)-imidazol-5-one
C16H12ClNO2S
