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CAS No.: | 102-65-8 |
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Name: | Sulfaclozine |
Article Data: | 3 |
Molecular Structure: | |
Formula: | C10H9ClN4O2S |
Molecular Weight: | 284.726 |
Synonyms: | Benzenesulfonamide,4-amino-N-(6-chloropyrazinyl)- (9CI);Sulfanilamide, N1-(6-chloropyrazinyl)-(7CI,8CI);Esb3 (antibiotic);N1-(6-Chloropyrazinyl)sulfanilamide;Sulfachloropyrazine;Sulfatyf; |
EINECS: | 203-044-0 |
Density: | 1.588 g/cm3 |
Melting Point: | 234.8-235.4 °C |
Boiling Point: | 495.7 °C at 760 mmHg |
Flash Point: | 253.6 °C |
Solubility: | soluble in water or methanol,slightly soluble in ethanol or acetone and not dissoluble in chloroform. |
Appearance: | Slightly yellow crystal powder |
PSA: | 106.35000 |
LogP: | 3.24800 |
4-amino-N-(6-chloropyrazin-2-yl)benzenesulfonamide
Conditions | Yield |
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With tin(II) chloride dihdyrate In ethanol at 80℃; for 0.5h; | 81% |
Conditions | Yield |
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Multi-step reaction with 2 steps 1: hydrogenchloride; pyridine / acetone / 20 °C / Sealed tube 2: tin(II) chloride dihdyrate / ethanol / 0.5 h / 80 °C View Scheme |
8-acetyl-7-hydroxy-4-methyl-2H-chromen-2-one
4-amino-N-(6-chloropyrazin-2-yl)benzenesulfonamide
Conditions | Yield |
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With acetic acid for 1h; Reflux; |
4-amino-N-(6-chloropyrazin-2-yl)benzenesulfonamide
Conditions | Yield |
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Multi-step reaction with 2 steps 1.1: hydrogenchloride; sodium nitrite / water / Cooling with ice 1.2: 0.25 h / Cooling with ice 2.1: ammonium hydroxide / water; ethanol / Heating View Scheme |
4-amino-N-(6-chloropyrazin-2-yl)benzenesulfonamide
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1.1: hydrogenchloride; sodium nitrite / water / Cooling with ice 1.2: 0.25 h / Cooling with ice 2.1: ammonium hydroxide / ethanol / Heating View Scheme |
4-amino-N-(6-chloropyrazin-2-yl)benzenesulfonamide
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1.1: hydrogenchloride; sodium nitrite / water / Cooling with ice 1.2: 0.25 h / Cooling with ice 2.1: ammonium hydroxide / ethanol / Heating View Scheme |
Conditions | Yield |
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Stage #1: 4-amino-N-(6-chloropyrazin-2-yl)benzenesulfonamide With hydrogenchloride; sodium nitrite In water Cooling with ice; Stage #2: 1-hydroxy-2-naphthoic acid With sodium hydroxide In water for 0.25h; Cooling with ice; |
IUPAC Name: 4-Amino-N-(6-chloropyrazin-2-yl)benzenesulfonamide
Empirical Formula: C10H9ClN4O2S
Molecular Weight: 284.7221
Einecs: 203-044-0
Freely Rotating Bonds: 2
Polar Surface Area: 74.78 Å2
Index of Refraction: 1.683
Molar Refractivity: 67.97 cm3
Molar Volume: 179.2 cm3
Polarizability: 26.94 ×10-24 cm3
Surface Tension: 83.3 dyne/cm
Density: 1.588 g/cm3
Flash Point: 253.6 °C
Enthalpy of Vaporization: 76.33 kJ/mol
Boiling Point: 495.7 °C at 760 mmHg
Vapour Pressure: 5.77E-10 mmHg at 25°C
The Cas Register Number of Sulfaclozine is 102-65-8.The chemical synonyms of Sulfaclozine (CAS NO.102-65-8) are N(sup 1)-(6-Chloropyrazinyl)sulfanilamide .The molecular structure of Sulfaclozine (CAS NO.102-65-8) is
.
Sulfaclozine (CAS NO.102-65-8) is used in organic synthesis.