Detail of "10453-89-1"

Reference

Evaluation of the genetic activity profiles of 65 pesticides

Evaluation of the genetic activity profiles of 65 pesticides. Garrett, Neil E.; Stack, H. Frank; Waters, Michael D. (Environ. Health Res. Test., Inc., Research Triangle Park, NC 27709, USA). Mutat. Res., 168(3), 301-25 (English) 1986. CODEN: MUREAV. ISSN: 0027-5107. DOCUMENT TYPE: Journal CA Section: 4 (Toxicology) The qual. profiles of genetic activity produced by pesticides and efforts to classify them according to their genotoxic effects and chem. structures are given. Three main categories may be distinguished based on the qual. results: category 1 pesticides were active in most of the in vitro and in vivo assays employed. These compds. include the structurally similar organophosphate insecticides, acephate [30560-19-1], demeton [8065-48-3], monocrotophos [6923-22-4], and trichlorfon [52-68-6]; the phthalimide fungicide analogs, captan (I) [133-06-2] and folpet [133-07-3]; and the thiocarbamate herbicide analogs, diallate [2303-16-4], sulfallate [95-06-7], and triallate [2303-17-5]. The category 2 compds. demonstrated fewer pos. results and may be subdivided into 2 parts, 1 of which contains 12 halogenated arom. or heterocyclic ring compds., including the phenoxy herbicides, 2,4-D [94-75-7], 2,4-DB [94-82-6], and 2,4,5-T [93-76-5]. The remaining part of category 2 consists of structurally similar organophosphate insecticides, azinphos-methyl [86-50-0], crotoxyphos [7700-17-6], disulfoton [298-04-4], and Me parathion [298-00-0]; three similar ethylenebisdithiocarbamate fungicides, maneb [12427-38-2], mancozeb [8018-01-7], and zineb [12122-67-7]; 3 similar pyrethroid insecticides, allethrin [584-79-2], chrysanthemic acid [10453-89-1], and Et chrysanthemate [97-41-6]; and 4 structurally diverse compds., cacodylic acid [75-60-5], dinoseb [88-85-7], sec-butylamine [13952-84-6], and benomyl [17804-35-2]. The 3rd category of pesticides gave neg. results in all tests and represents structurally diverse compds. Using the computerized profile matching methodol., from 2080 possible pairwise chem. combinations of the 65 pesticides, 20 statistically significant pairs were selected. The matches showed excellent qual. and, in most cases, excellent quant. agreement. Hence, it appears that specific patterns of test results present in the genetic activity profiles are related directly to chem.Except for chemicals metioned above, 52-68-6 and 298-02-2 are also used. structure. .

Analysis of pyrethroids on grains

Analysis of pyrethroids on grains. Desmarchelier, J.Some chemicals with cas registry numbers like 497-95-0 and 26002-80-2 are also used. M. (Div. Entomol., CSIRO, Canberra, Aust.). J. Stored Prod. Res., 12(4), 245-52 (English) 1976. CODEN: JSTPAR. DOCUMENT TYPE: Journal CA Section: 17 (Foods) Section cross-reference(s): 5 Two general procedures involving chromatog. and colorimetry are outlined for detn. of pyrethroid derivs. of chrysanthemic acid [10453-89-1] on wheat, wheat milling fractions, polished rice, corn, sorghum, oats and barley. Although limits of detection ranged upwards from 0.02 .mu.g, residues in the range 0.1-4 ppm were readily detd. with inexpensive equipment after suitable clean-up procedures. Wheat treated some months before anal. with bioresmethrin [28434-01-7] was analyzed by the 2 general procedures for derivs. of chrysanthemic acid, and also by 2 procedures specific for detn. of bioresmethrin. Results from all 4 procedures were comparable. One of the procedures for identification of chrysanthemic acid also enabled identification of pyrethroid derivs. of chrysanthemumdicarboxylic acid [497-95-0] and 3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylic acid [55701-05-8]. Thus, a wide range of commodities can be screened for the presence of com. pyrethroids. In addn., anal. studies on individual pyrethroids can be performed by use of a general method. .