Detail of "

1131-01-7

CAS Number:
1131-01-7
Name:
Acetamide, 2-chloro-N-(2,6-dimethylphenyl)-
Superlist Name:
2-Chloro-N-(2,6-dimethylphenyl)acetamide
Molecular Structure:
Formula:
C₁₀H₁₂ClNO
Molecular Weight:
197.66
Synonyms:
Chloroacetamido-2,6-xylidine;2,6-Acetoxylidide, 2-chloro- (8CI);2-Chloro-2,6-acetoxylidide;[(2,6-Dimethylphenyl)-aminocarbonylmethyl] chloride;N-(Chloroacetyl)-2,6-diethylaniline;N-Chloracetyl-2,6-dimethylaniline;2-Chloroaceto-2,6-xylidide;1-Chloroacetylamino-2,6-dimethylbenzene;N-Chloroacetyl-2,6-dimethylaniline;2-Chloro-2,6-dimethylacetanilide;2,6-Acetoxylidide, 2-chloro-;Chloroaceto-2,6-xylidide;Acetamide, 2-chloro-N- (2,6-dimethylphenyl)-;1-Chloroacetylamino-2,6-dimethylbenzene;alpha-Chloro-2,6-dimethylacetanilide;
EINECS:
214-460-7
Density:
1.187 g/cm³
Melting Point:
143-148 °C
Boiling Point:
316.766 °C at 760 mmHg
Flash Point:
145.375 °C
Appearance:
beige needles or crystalline powder
Hazard Symbols:
Xi
Risk Codes:
36/37/38
Safety:
26-37/39 Details

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Reference

Pharmaceutical local anesthetic composition: Pharmaceutical local anesthetic composition. Adams, Herbert J. F.; Takman, Bertil H. (Astra Pharmaceutical Products, Inc., USA). U. 1131-01-7 are also occured in this study.S. US 4029794 14 Jun 1977, 9 pp. Division of U.S. 3,957,996. (English). (United States of America). CODEN: USXXAM. CLASS: IC: A61K031-52. NCL: 424253000. APPLICATION: US 71-109942 26 Jan 1971. DOCUMENT TYPE: Patent CA Section: 1 (Pharmacodynamics) Section cross-reference(s): 25 Injectable compns. having a long-lasting anesthetic effect comprise a carrier, saxitoxin (I) (0.5-10 .mu.g/mL carrier), an aminoalkyl benzoate local anesthetic (0.05-5% of carrier wt.) and optionally a vasoconstrictor. Xylidene alkylaminoalkoxy derivs. are prepd. and also show long-lasting anesthetic activity in mixts. with I. The presence of I does not increase the general toxicity of the local anesthetics. For example, 2-chloro-2',6'-acetoxylidide [1131-01-7] was treated with sec-butylamine [13952-84-6] to give 2-(sec-butylamino)-2',6'-acetoxylidide [60119-83-7] which was then heated with Et2SO4 to give 2-(N-ethyl-N-sec-butylamino)-2',6'-acetoxylidide) (II) [60119-82-6]. A mixt. [63871-14-7] of 2 .mu.g/mL I and 0.5% II produced sciatic nerve blocks of 195 min mean duration in 5 of 6 mice compared to no blocks produced by I and 45 min blocks in 2 of 6 mice produced by II at the same individual dosages. .

Improvements on the experiment of preparing lidocaine: All Rights Reserved. Improvements on the experiment of preparing lidocaine. Kuang, Chun-tao; Hu, Ai-xi; Liu, Shen (College of Industry, Central South Forestry Univ., Changsha 410004, Peop. Rep. China). Shiyanshi Yanjiu Yu Tansuo, 25(2), 223-224 (Chinese) 2006 Shiyanshi Yanjiu Yu Tansuo Bianjibu.In this article, certain chemicals are used. Some of their cas registry numbers are 1131-01-7 and 87-62-7 CODEN: SYYTAZ. ISSN: 1006-7167. DOCUMENT TYPE: Journal CA Section: 20 (History, Education, and Documentation) Section cross-reference(s): 25 Optimizing process conditions for the synthesis of a-chloro-2,6-dimethylaniline [intermediate of lidocaine; 2-(diethylamino)-N-(2,6-dimethylphenyl)acetamide], using toluene-Na2CO3 soln. as solvent and the reaction time for 1.5h at 20-35°, were obtained by guiding students to perform inquiry-learning. The improved expt. is easily operated and controlled and the yield is over 90%. .

1131-01-7

Acetamide, 2-chloro-N-(2,6-dimethylphenyl)-

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CAS No.1131-01-7 2-Chloro-N-(2,6-dimethylphenyl)acetamide

CAS No.1131-01-7 2-Chloro-N-(2,6-dimethylphenyl)acetamide

CAS No.1131-01-7 2-Chloro-N-(2,6-dimethylphenyl)acetamide

CAS No.1131-01-7 2-Chloro-N-(2,6-dimethylphenyl)acetamide

CAS No.1131-01-7 2-Chloro-N-(2,6-dimethylphenyl)acetamide

CAS No.1131-01-7 2-Chloro-N-(2,6-dimethylphenyl)acetamide

CAS No.1131-01-7 2-Chloro-N-(2,6-dimethylphenyl)acetamide

CAS No.1131-01-7 2-Chloro-N-(2,6-dimethylphenyl)acetamide

CAS No.1131-01-7 2-Chloro-N-(2,6-dimethylphenyl)acetamide

CAS No.1131-01-7 2-Chloro-N-(2,6-dimethylphenyl)acetamide

CAS No.1131-01-7 2-Chloro-N-(2,6-dimethylphenyl)acetamide

CAS No.1131-01-7 2-Chloro-N-(2,6-dimethylphenyl)acetamide

CAS No.1131-01-7 2-Chloro-N-(2,6-dimethylphenyl)acetamide

CAS No.1131-01-7 2-Chloro-N-(2,6-dimethylphenyl)acetamide

CAS No.1131-01-7 2-Chloro-N-(2,6-dimethylphenyl)acetamide

CAS No.1131-01-7 2-Chloro-N-(2,6-dimethylphenyl)acetamide

CAS No.1131-01-7 2-Chloro-N-(2,6-dimethylphenyl)acetamide

CAS No.1131-01-7 2-Chloro-N-(2,6-dimethylphenyl)acetamide

CAS No.1131-01-7 2-Chloro-N-(2,6-dimethylphenyl)acetamide

CAS No.1131-01-7 2-Chloro-N-(2,6-dimethylphenyl)acetamide

CAS No.1131-01-7 2-Chloro-N-(2,6-dimethylphenyl)acetamide

CAS No.1131-01-7 2-Chloro-N-(2,6-dimethylphenyl)acetamide

CAS No.1131-01-7 2-Chloro-N-(2,6-dimethylphenyl)acetamide

CAS No.1131-01-7 2-Chloro-N-(2,6-dimethylphenyl)acetamide

CAS No.1131-01-7 2-Chloro-N-(2,6-dimethylphenyl)acetamide

CAS No.1131-01-7 2-Chloro-N-(2,6-dimethylphenyl)acetamide

CAS No.1131-01-7 2-Chloro-N-(2,6-dimethylphenyl)acetamide

CAS No.1131-01-7 2-Chloro-N-(2,6-dimethylphenyl)acetamide

CAS No.1131-01-7 2-Chloro-N-(2,6-dimethylphenyl)acetamide

CAS No.1131-01-7 2-Chloro-N-(2,6-dimethylphenyl)acetamide

CAS No.1131-01-7 2-Chloro-N-(2,6-dimethylphenyl)acetamide

CAS No.1131-01-7 2-Chloro-N-(2,6-dimethylphenyl)acetamide

Reference