CAS No.122852-75-9,1H-Pyrido[4,3-b]indol-1-one,2,3,4,5-tetrahydro-5-methyl- Suppliers

Detail of "122852-75-9"

CAS Number:

122852-75-9

Name:

Superlist Name:

Molecular Structure:

Formula:

C₁₂H₁₂N₂O

Molecular Weight:

200.24

Synonyms:

5-methyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indol-1-one;

Density:

1.316 g/cm³

Boiling Point:

508.047 °C at 760 mmHg

Flash Point:

261.057 °C

Preparation of 2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indol-1-ones: Preparation of 2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indol-1-ones. Whitehead, John William Frank; Mills, Keith; Coates, Ian Harold; Oxford, Alexander William; North, Peter Charles (Glaxo Group Ltd., UK). Eur. Pat. Appl. EP 458624 A1 27 Nov 1991, 10 pp. DESIGNATED STATES: R: AT, BE, CH, DE, DK, ES, FR, GB, IT, LI, NL, SE. (European Patent Organization). CODEN: EPXXDW. CLASS: ICM: C07D471-04. ICS: C07D211-86; A61K031-44. ICI: C07D471-04, C07D221-00, C07D209-00. APPLICATION: EP 91-304642 22 May 1991. PRIORITY: GB 90-11469 23 May 1990. DOCUMENT TYPE: Patent CA Section: 27 (Heterocyclic Compounds (One Hetero Atom)) Title compds.There are some commonly used reagents with their cas registry numbers 122852-75-9 and 139122-76-2 in this article. (I; R = H, Me, Et; R1 = H) were prepd. as pharmaceutical intermediate by cyclization of phenylhydrazinotetrahydropyridinones II (R as above). Thus, PhNMeNH2 was condensed with 2,4-piperidinedione to give II (R = Me) which was treated with concd. H2SO4 to give I (R = Me, R1 = H). The latter was condensed with 4-hydroxymethyl-5-methylimidazole hydrochloride to give I (R = Me, R1 = 5-methyl-1H-imidazol-4-ylmethyl), a 5-HT3 antagonist. .

Detail of "122852-75-9"