CAS No.1229-35-2,METHDILAZINE HYDROCHLORIDE (200 MG) Suppliers

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Basic Information

Molecular Structure:
CAS No.:	1229-35-2
Name:	METHDILAZINE HYDROCHLORIDE (200 MG)

Formula:	C18H20 N2 S . Cl H
Molecular Weight:	332.92
Synonyms:	10H-Phenothiazine,10-[(1-methyl-3-pyrrolidinyl)methyl]-, monohydrochloride (9CI); Phenothiazine,10-[(1-methyl-3-pyrrolidinyl)methyl]-, monohydrochloride (8CI); Dilosyn;Disyncran; Methdilazine hydrochloride; Methdilazine monohydrochloride; NSC169091; Tacaryl; Tacaryl hydrochloride
Density:	g/cm³
Melting Point:	187.5-189°
Boiling Point:	430.4°Cat760mmHg
Flash Point:	214.1°C
Safety:	Poison by ingestion, intravenous, and intraperitoneal routes. Mutation data reported. Experimental reproductive effects. An antihistamine. When heated to decomposition it emits very toxic fumes of NO_x and HCl.
PSA:	31.78000
LogP:	5.04590

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Chemistry

IUPAC Name: 10-[(1-Methylpyrrolidin-3-yl)methyl]phenothiazine hydrochloride
Synonyms: 10-[(1-Methyl-3-pyrrolidinyl)methyl]-10H-phenothiazine hydrochloride (1:1) ; 10-[(1-Methyl-3-pyrrolidinyl)methyl]phenothiazine hydrochloride ; 10-[(1-Methylpyrrolidin-3-yl)methyl]-10H-phenothiazine hydrochloride ; 10-[(1-Methylpyrrolidin-3-yl)methyl]-10H-phenothiazine hydrochloride (1:1) ; 10H-Phenothiazine, 10-[(1-Methyl-3-pyrrolidinyl)methyl]-, hydrochloride (1:1)
CAS NO: 1229-35-2
Molecular Formula of Methdilazine hydrochloride (CAS NO.1229-35-2) : C₁₈H₂₁ClN₂S
Molecular Weight of Methdilazine hydrochloride (CAS NO.1229-35-2) : 332.89074
Molecular Structure of Methdilazine hydrochloride (CAS NO.1229-35-2) :
EINECS: 214-967-3
Mol File: 1229-35-2.mol
Flash Point: 214.1 °C
Enthalpy of Vaporization: 68.58 kJ/mol
Boiling Point: 430.4 °C at 760 mmHg
Vapour Pressure: 1.3E-07 mmHg at 25°C
General Description White microcrystalline powder with a slight odor. pH (1% aqueous solution) 4.8-6.
Air & Water Reactions: Water soluble. pH (1% aqueous solution) 4.8-6 .

Toxicity Data With Reference

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
dog	LDLo	intravenous	25mg/kg (25mg/kg)	BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: DYSPNEA	Toxicology and Applied Pharmacology. Vol. 2, Pg. 68, 1960.
guinea pig	LD50	oral	263mg/kg (263mg/kg)		Toxicology and Applied Pharmacology. Vol. 2, Pg. 68, 1960.
mouse	LD50	intraperitoneal	100mg/kg (100mg/kg)	BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: DYSPNEA	Toxicology and Applied Pharmacology. Vol. 2, Pg. 68, 1960.
mouse	LD50	oral	190mg/kg (190mg/kg)	BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: DYSPNEA	Toxicology and Applied Pharmacology. Vol. 2, Pg. 68, 1960.
mouse	LDLo	intramuscular	300mg/kg (300mg/kg)		Therapie. Vol. 15, Pg. 1064, 1960.
mouse	LDLo	intravenous	25mg/kg (25mg/kg)		Therapie. Vol. 15, Pg. 1064, 1960.
rabbit	LD50	intravenous	17mg/kg (17mg/kg)	BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: DYSPNEA	Toxicology and Applied Pharmacology. Vol. 2, Pg. 68, 1960.
rat	LD50	oral	260mg/kg (260mg/kg)	BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: DYSPNEA	Toxicology and Applied Pharmacology. Vol. 2, Pg. 68, 1960.
rat	LDLo	intraperitoneal	75mg/kg (75mg/kg)		Therapie. Vol. 15, Pg. 1064, 1960.
rat	LDLo	intravenous	22mg/kg (22mg/kg)		Therapie. Vol. 15, Pg. 1064, 1960.

Safety Profile

Poison by ingestion, intravenous, and intraperitoneal routes. Mutation data reported. Experimental reproductive effects. An antihistamine. When heated to decomposition it emits very toxic fumes of NO_x and HCl.

Specification

Reactivity Profile: Methdilazine hydrochloride (200 MG) is sensitive to exposure to light. An acidic salt. Materials in this group are generally soluble in water. The resulting solutions contain moderate concentrations of hydrogen ions and have pH's of less than 7.0. They react as acids to neutralize bases. These neutralizations generate heat, but less or far less than is generated by neutralization of inorganic acids, inorganic oxoacids, and carboxylic acid. They usually do not react as either oxidizing agents or reducing agents but such behavior is not impossible.