Name: (R)-3-Aminopentanoic acid
SKU: 131347-76-7

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Basic Information

Molecular Structure:
CAS No.:	131347-76-7
Name:	(R)-3-Aminopentanoic acid
Article Data:	7

Formula:	C₅H₁₁NO₂
Molecular Weight:	117.148
Synonyms:	Pentanoicacid, 3-amino-, (R)-;(-)-3-Aminopentanoic acid;
Density:	1.067 g/cm³
Boiling Point:	230.142 °C at 760 mmHg
Flash Point:	92.987 °C
Appearance:	Colorless to pale yellow liquid
PSA:	63.32000
LogP:	0.89870

Synthetic route

Conditions	Yield
With hydrogen; palladium dihydroxide In methanol for 3h; Ambient temperature;	95%
With hydrogen; palladium dihydroxide In methanol for 3h; Ambient temperature;	95%

Conditions	Yield
With trifluoroacetic acid In dichloromethane at 20℃; for 2h;	89%

Conditions	Yield
With hydrogen bromide; methyloxirane; phenol 1) reflux, 4 h; Yield given. Multistep reaction;
With hydrogen bromide; methyloxirane 1.) phenol, reflux, 4 h, 2.) EtOH, reflux, 2 h; Yield given. Multistep reaction;

Conditions	Yield
Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;

Conditions	Yield
With hydrogen; palladium on activated charcoal In ethanol at 20℃; under 3800 Torr;

: 911224-72-1
tert-butyl (3R,αR)-3-(N-benzyl-N-α-methylbenzylamino)pentanoate

Conditions	Yield
Multi-step reaction with 2 steps 1: 95 percent / H2 / Pd/C / methanol / 50 °C / 3800 Torr 2: 89 percent / TFA / CH2Cl2 / 2 h / 20 °C View Scheme

Conditions	Yield
Multi-step reaction with 3 steps 1: 92 percent / n-BuLi / tetrahydrofuran; hexane / -78 °C 2: 95 percent / H2 / Pd/C / methanol / 50 °C / 3800 Torr 3: 89 percent / TFA / CH2Cl2 / 2 h / 20 °C View Scheme

Conditions	Yield
Multi-step reaction with 2 steps 1: 67 percent / n-BuLi / tetrahydrofuran; hexane / -78 °C 2: H2 / Pd/C / ethanol / 20 °C / 3800 Torr View Scheme

Conditions	Yield
Multi-step reaction with 2 steps 1: 93 percent / K2CO3 / methanol; H2O / 24 h / Ambient temperature 2: 1.) 47percent aq. HBr, 2.) methyloxirane / 1.) phenol, reflux, 4 h, 2.) EtOH, reflux, 2 h View Scheme
Multi-step reaction with 2 steps 1: 93 percent / K2CO3 / methanol; H2O / 24 h / 25 °C 2: 1) PhOH, 47percent aq. HBr, 2) epoxypropane / 1) reflux, 4 h View Scheme

Conditions	Yield
Multi-step reaction with 2 steps 1: 91 percent / conc. aq. HCl / 3 h / 80 °C 2: 95 percent / H2 / 20percent Pd(OH)2/C / methanol / 3 h / Ambient temperature View Scheme
Multi-step reaction with 2 steps 1: 90 percent / conc. aq. HCl / 3 h / Heating 2: 95 percent / H2 / Pd(OH)2/C / methanol / 3 h / Ambient temperature View Scheme

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