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Detail of "13171-25-0"

  • CAS Number:
  • 13171-25-0
  • Name:
  • Trimetazidine dihydrochloride

  • Molecular Structure:
  • Formula:
  • C14H24Cl2N2O3
  • Molecular Weight:
  • 339.26
  • Synonyms:
  • Piperazine, 1-(2,3,4-trimethoxybenzyl)-, dihydrochloride;Kyurinett;Piperazine, 1-((2,3,4-trimethoxyphenyl)methyl)-, dihydrochloride (9CI);1-[(2,3,4-trimethoxyphenyl)methyl]-2,3,5,6-tetrahydropyrazine;1-[(2,3,4-trimethoxyphenyl)methyl]piperazine dihydrochloride;Trimetajust;Lubomail;Piperazine,1-[(2,3,4-trimethoxyphenyl)methyl]-,dihydrochloride;Prestwick_871;S 4004;
  • EINECS:
  • 236-117-0
  • Melting Point:
  • 231-235 °C
  • Boiling Point:
  • 364 °C at 760 mmHg
  • Flash Point:
  • 174 °C
  • Appearance:
  • crystalline solid
  • Hazard Symbols:
  • IrritantXi,HarmfulXn
  • Risk Codes:
  • 22-36/37/38
  • Safety:
  • 26-36 Details

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CAS No.13171-25-0 Trimetazidine dihydrochlorideCompetitive Product

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CAS No.13171-25-0 Trimetazidine dihydrochloride

Assay:99%  Appearance:white powder  Package:25kg/drumStorage:Ventilating ...  Transportation:by air/by se...  Application:Food &feed a...

Trimetazidine dihydrochloride 13171-25-0 Synonyms 1-(2,3,4-Trimethoxybenzyl)piperazine dihydrochloride; Molecular Formula C14H22N2O3.2HCl;C14H24Cl2N2O3 Molecular Weight 303.80 CAS Registry Number 13171-25-0 EINECS 236-117-0

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CAS No.13171-25-0 Trimetazidine dihydrochloride

Trimetazidine dihydrochloride 13171-25-0 Synonyms 1-(2,3,4-Trimethoxybenzyl)piperazine dihydrochloride; Molecular Formula C14H22N2O3.2HCl;C14H24Cl2N2O3 Molecular Weight 303.80 CAS Registry Number 13171-25-0 EINECS 236-117-0

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CAS No.13171-25-0 Trimetazidine dihydrochloride

Trimetazidine HCL---We supply this product in very competitive price.

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CAS No.13171-25-0 Trimetazidine dihydrochloride

Assay:99%  Appearance:white or alm...  Package:25kg/cardboa...Storage:stored and p...  Transportation:by sea/air  Application:anti-angina

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CAS No.13171-25-0 Trimetazidine dihydrochloride

Formula: C14H22N2O3.2HCl Molecular Weight: 303.80 Standard: Enterprise Standard Assay: 98.5~101.5%

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Reference

Preparation of 1-(2,3,4-trimethoxybenzyl)piperazine by reductive amination
Preparation of 1-(2,3,4-trimethoxybenzyl)piperazine by reductive amination. Souvie, Jean Claude (ADIR et Cie., Fr.). Eur. Pat. Appl.There are some reagents with their cas registry numbers 13171-25-0 and 110-85-0 are used in this study. EP 453365 A1 23 Oct 1991, 7 pp. DESIGNATED STATES: R: AT, BE, CH, DE, DK, ES, FR, GB, GR, IT, LI, LU, NL, SE. (European Patent Organization). CODEN: EPXXDW. CLASS: ICM: C07D295-096. APPLICATION: EP 91-401025 18 Apr 1991. PRIORITY: FR 90-5027 20 Apr 1990. DOCUMENT TYPE: Patent CA Section: 28 (Heterocyclic Compounds (More Than One Hetero Atom)) Title compd. (trimetazidine) was prepd. by condensation of 2,3,4-(Me)3C6H2CHO with piperazine followed by hydrogenation of the intermediate without isolation. .
Quantification of trimetazidine in human plasma by liquid chromatography-electrospray ionization mass spectrometry and its application to a bioequivalence study
All Rights Reserved. Quantification of trimetazidine in human plasma by liquid chromatography-electrospray ionization mass spectrometry and its application to a bioequivalence study. Wang, Z. B.; Sun, J.; Rong, R.; Tang, J. L.; He, Zhonggui G. ( Department of Biopharmaceutics, School of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, Peop. Rep. China). Pharmazie, 62(1), 27-30 (English) 2007 Govi-Verlag Pharmazeutischer Verlag GmbH. CODEN: PHARAT. ISSN: 0031-7144. DOCUMENT TYPE: Journal CA Section: 1 (Pharmacology) A rapid, sensitive and specific liq. chromatog.-electrospray ionization mass spectrometric (LC-ESI-MS) method was developed for the quantification of trimetazidine in human plasma.There are some reagents with their cas registry numbers 5011-34-7 and 13171-25-0 are used in this study. The analyte and the internal std. (pseudoephedrine) were extd. from plasma samples with n-hexane-dichloromethane (1:1, vol./vol.) and analyzed on a C18 column. The chromatog. sepn. was achieved within 3.5 min using the mobile phase consisting of methanol/0.05% formic acid (, vol./vol.) and the flow rate was 1.0 mL/min. Ion signals m/z 181.0 and 148.0 were measured in the pos. mode for trimetazidine and pseudoephedrine, resp. The calibration curves were linear within the range of 0.4 ~ 120 ng/mL. The lower limit of quantification (LLOQ) was 0.4 ng/mL with 0.5 mL plasma sample. The intra- and inter-day precisions were lower than 12% in terms of relative std. deviation (RSD). The inter-day relative error (RE) as detd. from quality control samples (QCs), ranged from -1.4% to 3.3%. This validated method was successfully applied to the bioequivalent evaluation of 2 brands of trimetazidine tablets in 20 healthy volunteers. .
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