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Detail of "1405-87-4"

  • MSDS Download
  • CAS Number:
  • 1405-87-4
  • Name:
  • Bacitracin

  • Molecular Structure:
  • Formula:
  • C66H103N17O16S
  • Molecular Weight:
  • 1422.69
  • Deleted CAS:
  • 12640-37-8|1405-75-0|60454-67-3
  • Synonyms:
  • Bacitracin (JP14/USP);Heptonamide,5-amino-2,5,6,7-tetradeoxy-N- [1-(3,4-dihydro-8-hydroxy-1-oxo-1H-2- benzopyran-3-yl)-3-methylbutyl]-2-methyl-;Bacitracin (TN);(4R)-4-[[(2S)-2-[[2-[(1S)-1-amino-2-methyl-butyl]4,5-dihydro-1,3-thiazole-5-carbonyl]amino]-4-methyl-pentanoyl]amino]-4-[[(1S)-1-[[(3S,6R,9S,12R,15S,18R,21S)-18-(3-aminopropyl)-12-benzyl-15-butan-2-yl-3-(carbamoylmethyl)-6-(carboxymethyl)-9-(3H-imidazol-4-ylmethyl)-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptazacyclopentacos-21-yl]carbamoyl]-2-methyl-butyl]carbamoyl]butanoic acid;Bacilliquin;Bacitracina;Bacitracin;Topitracin;Agfivin;Altracin;Bacitracin A;
  • EINECS:
  • 215-786-2
  • Density:
  • 1.43 g/cm3
  • Melting Point:
  • 221-225 °C
  • Boiling Point:
  • 1750.1 °C at 760 mmHg
  • Flash Point:
  • 1012.2 °C
  • Solubility:
  • soluble in water: 50 mg/mL
  • Appearance:
  • white to almost white powder
  • Safety:
  • 24/25 Details

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CAS No.1405-87-4 BacitracinCompetitive Product

Assay:Not less tha...  Appearance:White to pal...  Package:2.5kg/tinStorage:Preserve in ...

Bacitracin Specification: USP33

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Bacitracin Bacillus licheniformis

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Assay:99.0% Min

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Assay:99%  Appearance:white powder...  Package:25kg /fiberd...

Bacitracin /1405-87-4 Cas no.:1405-87-4 Assay:99% min Appearance:white powder or crystalline Bacitracin /1405-87-4 Cas no.:1405-87-4 Assay:99% min Appearance:white powder or crystalline

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Reference

Transglutaminase activity in pancreatic islets
Transglutaminase activity in pancreatic islets. Gomis, R.; Sener, A.; Malaisse-Lagae, F.; Malaisse, W. J. (Lab. Exp. Med., Brussels Univ., Brussels B-1000, Belg.).Several reagents with their cas registry numbers 9004-10-8 and 80146-85-6 are used here. Biochim. Biophys. Acta, 760(3), 384-8 (English) 1983. CODEN: BBACAQ. ISSN: 0006-3002. DOCUMENT TYPE: Journal CA Section: 2 (Mammalian Hormones) Pancreatic islet homogenates catalyze, in a Ca2+-dependent fashion, the incorporation of histamine, putrescine, agmatine, methylamine, and L-lysine into N,N-dimethylcasein. With histamine as the amine donor, the Km values for Ca2+ and histamine were 90 mM and 0.7 mM, resp. The incorporation of histamine into N,N-dimethylcasein is inhibited by monodansylcadaverine, N-p-tosyl glycine, bacitracin, and methylamine, the relative extent of inhibition depending on the resp. concns. of Ca2+, inhibitor, and amine donor. Bacitracin and methylamine, but not N-p-tosyl glycine, cause a dose-related inhibition of glucose-stimulated insulin [9004-10-8] release. In pancreatic islets, the Ca2+-responsive transglutaminase [80146-85-6] activity apparently plays a crit. role in the process of glucose-induced insulin release. .
Characteristics of cholecystokinin release from rat brain: effects of bacitracin and ionic requirements
Characteristics of cholecystokinin release from rat brain: effects of bacitracin and ionic requirements. Sheehan, M. J.; De Belleroche, J.In this study, 9011-97-6 and 7440-09-7 are also used. (Dep. Biochem., Charing Cross Hosp. Med. Sch., London W6 8RF, UK). Biochem. Soc. Trans., 11(2), 213-14 (English) 1983. CODEN: BCSTB5. ISSN: 0300-5127. DOCUMENT TYPE: Journal CA Section: 2 (Mammalian Hormones) Section cross-reference(s): 1 Cholecystokinin (I) [9011-97-6] release by tissue slices from rat cerebral cortex, corpus striatum, nucleus accumbens, and dorsal hippocampus was elevated in a concn.-dependent manner by bacitracin (II) [1405-87-4], a 3-fold elevation being obtained at 0.3 mM II, rising to 20-fold at 1 mM. The release of I from cerebral cortex slices in the presence of II (1 mM) was stimulated above resting values by K+ concns. of 330 mM. The response to K+ increased steeply up to 40 mM K+, where a 20-fold stimulation of release was obtained, and this increase remained const. up to 60 mM K. No evoked release of I occurred in the absence of Ca2+. .
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