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Detail of "144809-28-9"

  • CAS Number:
  • 144809-28-9
  • Name:

  • 2,4-Thiazolidinedione,5-[[4-[2-(5-ethyl-2-pyridinyl)ethoxy]phenyl]methylene]-

  • Superlist Name:
  • 5-{4-[2-(5-Ethyl-2-pyridinyl)ethoxyl]benzyldene}-2,4-thiazolidinedione
  • Molecular Structure:
  • Formula:
  • C19H18N2O3S
  • Molecular Weight:
  • 354.42
  • Synonyms:
  • 5-[4-[2-(5-Ethyl-2-pyridinyl)ethoxy]benzylidene]-1,3-thiazolidine-2,4-dione;5-[4-[2-(5-Ethyl-2-pyridyl)ethoxy]benzylidene]thiazolidine-2,4-dione;5-[4-[2-(5-Ethylpyridin-2-yl)ethoxy]benzylidene]thiazolidine-2,4-dione;
  • Density:
  • 1.301 g/cm3
  • Appearance:
  • white solid
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CAS No.144809-28-9 5-{4-[2-(5-Ethyl-2-pyridinyl)ethoxyl]benzyldene}-2,4-thiazolidinedione

Supplier:Anhui Charm Imp.&Exp.Co., Ltd [ China (Mainland)]

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CAS No.144809-28-9 5-{4-[2-(5-Ethyl-2-pyridinyl)ethoxyl]benzyldene}-2,4-thiazolidinedione

Assay:98%

Supplier:Hangzhou Dayangchem Co., Ltd. [ China (Mainland)]

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CAS No.144809-28-9 5-{4-[2-(5-Ethyl-2-pyridinyl)ethoxyl]benzyldene}-2,4-thiazolidinedione

intermediate of Pioglitazone

Supplier:ORCHID CHEMICAL SUPPLIES LTD (OCS) [ China (Mainland)]

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CAS No.144809-28-9 5-{4-[2-(5-Ethyl-2-pyridinyl)ethoxyl]benzyldene}-2,4-thiazolidinedione

Supplier:LIDE PHARMACEUTICALS LIMITED [ China (Mainland)]

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CAS No.144809-28-9 5-{4-[2-(5-Ethyl-2-pyridinyl)ethoxyl]benzyldene}-2,4-thiazolidinedione

Supplier:Shijiazhuang Xudao Chemical Co.,Ltd [ China (Mainland)]

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CAS No.144809-28-9 5-{4-[2-(5-Ethyl-2-pyridinyl)ethoxyl]benzyldene}-2,4-thiazolidinedione

Supplier:ChemOrganic Limited [ China (Mainland)]

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CAS No.144809-28-9 5-{4-[2-(5-Ethyl-2-pyridinyl)ethoxyl]benzyldene}-2,4-thiazolidinedione

Supplier:Zhejiang Chemline International Co., Ltd. [ China (Mainland)]

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CAS No.144809-28-9 5-{4-[2-(5-Ethyl-2-pyridinyl)ethoxyl]benzyldene}-2,4-thiazolidinedione

Supplier:Hangzhou utanpharma Co., Ltd [ China (Mainland)]

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CAS No.144809-28-9 5-{4-[2-(5-Ethyl-2-pyridinyl)ethoxyl]benzyldene}-2,4-thiazolidinedione

Production:

Supplier:GreatAp Chemicals Co.Ltd. [ China (Mainland)]

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CAS No.144809-28-9 5-{4-[2-(5-Ethyl-2-pyridinyl)ethoxyl]benzyldene}-2,4-thiazolidinedione

5-{4-[2-(5-ethyl-2-pyridyl)ethoxy]benzylidene}-2,4-thiazolidinedione

Supplier:Cangzhou Senary Chemical Science-tech Co., Ltd [ China (Mainland)]

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CAS No.144809-28-9 5-{4-[2-(5-Ethyl-2-pyridinyl)ethoxyl]benzyldene}-2,4-thiazolidinedione

Supplier:S.V.Enterprises [ India]

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CAS No.144809-28-9 5-{4-[2-(5-Ethyl-2-pyridinyl)ethoxyl]benzyldene}-2,4-thiazolidinedione

Supplier:Niralee Pharma Inc [ India]

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CAS No.144809-28-9 5-{4-[2-(5-Ethyl-2-pyridinyl)ethoxyl]benzyldene}-2,4-thiazolidinedione

Supplier:SNAP INTERMEDIATES [ India]

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CAS No.144809-28-9 5-{4-[2-(5-Ethyl-2-pyridinyl)ethoxyl]benzyldene}-2,4-thiazolidinedione

5-[4-(2-(2-(5-ETHYL-2-PYRIDINYL) ETHOXY) PHENYL) METHYLENE] -2,4- HIAZOLIDINEDIONE

Supplier:Saraf Chemicals Ltd [ India]

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CAS No.144809-28-9 5-{4-[2-(5-Ethyl-2-pyridinyl)ethoxyl]benzyldene}-2,4-thiazolidinedione

5-{4-[2-(5-ethyl-2-pyridinyl)ethoxyl]benzyldene}-2,4-thiazolidinedione

Supplier:Manus Aktteva Biopharma LLP [ India]

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CAS No.144809-28-9 5-{4-[2-(5-Ethyl-2-pyridinyl)ethoxyl]benzyldene}-2,4-thiazolidinedione

Supplier:Qihe Zhongzhi Chemical.Co.,Ltd [ China (Mainland)]

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CAS No.144809-28-9 5-{4-[2-(5-Ethyl-2-pyridinyl)ethoxyl]benzyldene}-2,4-thiazolidinedione

Supplier:Cangzhou Goldlion Chemicals Co., Ltd [ China (Mainland)]

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CAS No.144809-28-9 5-{4-[2-(5-Ethyl-2-pyridinyl)ethoxyl]benzyldene}-2,4-thiazolidinedione

Supplier:Shanghai Maigochem Co., Ltd. [ China (Mainland)]

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CAS No.144809-28-9 5-{4-[2-(5-Ethyl-2-pyridinyl)ethoxyl]benzyldene}-2,4-thiazolidinedione

Supplier:Zhangjiakou Gerui Biochemical Technology Co., Ltd [ China (Mainland)]

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CAS No.144809-28-9 5-{4-[2-(5-Ethyl-2-pyridinyl)ethoxyl]benzyldene}-2,4-thiazolidinedione

Supplier:S. N. Chemicals [ India]

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Reference

A novel process to prepare pioglitazone via several novel intermediates
A novel process to prepare pioglitazone via several novel intermediates. Pandey, Bipin; Lohray, Vidya Bhushan; Lohray, Braj Bhushan (Cadila Healthcare Limited, India). PCT Int. Appl. WO 2004007490 A2 22 Jan 2004, 74 pp. DESIGNATED STATES: W: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW, AM, AZ, BY, KG, KZ, MD, RU; RW: AT, BE, BF, BJ, CF, CG, CH, CI, CM, CY, DE, DK, ES, FI, FR, GA, GB, GR, IE, IT, LU, MC, ML, MR, NE, NL, PT, SE, SN, TD, TG, TR. (English). (World Intellectual Property Organization). CODEN: PIXXD2. CLASS: ICM: C07D417-00. APPLICATION: WO 2003-IN241 15 Jul 2003. PRIORITY: IN 2002-MU648 16 Jul 2002. DOCUMENT TYPE: Patent CA Section: 28 (Heterocyclic Compounds (More Than One Hetero Atom)) Section cross-reference(s): 1, 63 The present invention discloses a novel and general process to prep. various pyridine substituted 5-[4-[2-(alkyl substituted pyridyl)ethoxy]benzyl]-2,4-thiazolidinone derivs. 110-86-1 and 144809-28-9 are cas registry numbers of chemicals which are used as reagents here. of general formula I [R = alkyl], and their pharmaceutically acceptable salts. The present invention esp. provides a novel process to prep. pioglitazone hydrochloride [R = 5-ethyl], via novel intermediates, i.e. II and III. This process involves lesser no. of steps with high yields and uses key solid intermediates, which are operationally simple, and therefore offers opportunities for better com. viability. .
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