Products Categories
Basic Information
| CAS No.: | 189035-22-1 |
|---|---|
| Name: | 6-BROMO-2,3-DIHYDRO-BENZOFURAN |
| Article Data: | 12 |
| Molecular Structure: | |
|
|
|
| Formula: | C8H7 Br O |
| Molecular Weight: | 199.047 |
| Synonyms: | 6-Bromo-2,3-dihydro-1-benzofuran;6-Bromo-2,3-dihydrobenzofuran |
| Density: | 1.582g/cm3 |
| Boiling Point: | 239.8°C at 760 mmHg |
| Flash Point: | 94.9°C |
| PSA: | 9.23000 |
| LogP: | 2.38400 |
Related products
- 483366-12-7(2S,4R)-1-Boc-2-cyano-4-hydroxypyrrolidine
- 361456-36-2METHYL (R)-(+)-ISOCYANATO-3-PHENYLPROPI&
- 5156-58-1N-(1-Benzyl-4-pipperidinyl)-N-phenylpropanamide HCl
- 81281-59-67-Benzylideneaminotheophylline
- 50288-62-5threo-Phenyl-2-piperidyl acetamide
- 82993-81-5D-threo-Ritalinic acid hydrochloride
- 47087-37-6Z-D-Glu-OMe
- 73441-42-6METHYL-5-CHLORO-2,2-DIMETHYLVALERATE
- 211914-50-0N-[[2-[[[4-(Aminoiminomethyl)phenyl]amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]-N-(2-pyridinyl)-beta-alanine ethyl ester hydrochloride
- 240444-70-62,3,5,6-Tetrafluor-4-(methoxymethyl)benzyl-2,2-dimethyl-3-(prop-1-en-1-yl)cyclopropancarboxylat
Synthetic route
- 377091-18-4
1,4-dibromo-2-(2-bromoethoxy)benzene
- 189035-22-1
6-bromo-2,3-dihydro-1-benzofuran
Conditions
| Conditions | Yield |
|---|---|
| With n-butyllithium In tetrahydrofuran; hexane at -78℃; for 4h; | 94% |
| With n-butyllithium In tetrahydrofuran; benzene at -78℃; for 1h; Inert atmosphere; | 85% |
| With n-butyllithium In tetrahydrofuran; benzene at -78℃; for 1h; Inert atmosphere; | 85% |
- 377091-17-3
1,4-dibromo-2-hydroxyethoxybenzene
- 189035-22-1
6-bromo-2,3-dihydro-1-benzofuran
Conditions
| Conditions | Yield |
|---|---|
| Stage #1: 1,4-dibromo-2-hydroxyethoxybenzene With phosphorus tribromide In toluene at 90℃; for 2.5h; Heating / reflux; Stage #2: With sodium hydroxide In water; toluene at 20℃; Stage #3: With n-butyllithium In tetrahydrofuran; hexane at -75℃; for 0.5h; | 40% |
| Multi-step reaction with 2 steps 1: phosphorus tribromide / toluene / 10 h / 90 °C 2: n-butyllithium / tetrahydrofuran; benzene / 1 h / -78 °C / Inert atmosphere View Scheme | |
| Multi-step reaction with 2 steps 1: phosphorus tribromide / toluene / 2.5 h / 20 - 90 °C 2: n-butyllithium / tetrahydrofuran; hexane / 2.5 h / -78 - 0 °C / Inert atmosphere View Scheme |
- 496-16-2
2,3-Dihydrobenzofuran
- 189035-22-1
6-bromo-2,3-dihydro-1-benzofuran
Conditions
| Conditions | Yield |
|---|---|
| With potassium hydroxide; bromine; potassium bromide at 20℃; |
- 189035-22-1
6-bromo-2,3-dihydro-1-benzofuran
Conditions
| Conditions | Yield |
|---|---|
| In n-heptane; dichloromethane; ethyl acetate |
- 28165-52-8
2,5-dibromophenol
- 189035-22-1
6-bromo-2,3-dihydro-1-benzofuran
Conditions
| Conditions | Yield |
|---|---|
| Multi-step reaction with 2 steps 1: sodium hydroxide / 40 h / 80 °C 2: n-butyllithium / hexane; tetrahydrofuran / 4 h / -78 °C View Scheme | |
| Multi-step reaction with 2 steps 1: potassium carbonate / acetonitrile / 4 h / 80 °C 2: n-butyllithium / tetrahydrofuran / 3 h / -100 °C View Scheme |
- 1435-52-5
2,5-dibromofluorobenzene
- 189035-22-1
6-bromo-2,3-dihydro-1-benzofuran
Conditions
| Conditions | Yield |
|---|---|
| Multi-step reaction with 3 steps 1: 1-methyl-pyrrolidin-2-one; potassium tert-butylate / 100 °C / Inert atmosphere 2: phosphorus tribromide / toluene / 10 h / 90 °C 3: n-butyllithium / tetrahydrofuran; benzene / 1 h / -78 °C / Inert atmosphere View Scheme | |
| Multi-step reaction with 3 steps 1: potassium tert-butylate / 1-methyl-pyrrolidin-2-one / 100 °C / Inert atmosphere 2: phosphorus tribromide / toluene / 10 h / 90 °C 3: n-butyllithium / tetrahydrofuran; benzene / 1 h / -78 °C / Inert atmosphere View Scheme | |
| Multi-step reaction with 3 steps 1: potassium tert-butylate; 1-methyl-pyrrolidin-2-one / 15 h / 20 - 100 °C 2: phosphorus tribromide / toluene / 2.5 h / 20 - 90 °C 3: n-butyllithium / tetrahydrofuran; hexane / 2.5 h / -78 - 0 °C / Inert atmosphere View Scheme |
- 189035-22-1
6-bromo-2,3-dihydro-1-benzofuran
- 1102467-17-3
5,6-dibromo-2,3-dihydro-1-benzofuran
Conditions
| Conditions | Yield |
|---|---|
| With N-Bromosuccinimide In acetonitrile at 20℃; for 3h; | 93% |
| With N-Bromosuccinimide In acetonitrile at 20℃; |
Conditions
| Conditions | Yield |
|---|---|
| Stage #1: potassium cyanide With acetic acid In ethylene glycol at 20℃; Sealed tube; Stage #2: 6-bromo-2,3-dihydro-1-benzofuran With P(t-Bu)3 Palladacycle Gen. 3; potassium acetate In 1,4-dioxane; water at 60℃; for 16h; Sealed tube; | 93% |
- 189035-22-1
6-bromo-2,3-dihydro-1-benzofuran
- 496047-46-2
7-(2-benzyloxy-4-methoxyphenyl)-6-tert-butoxycarbonyl-5-oxocyclopenta-1,3-dieno[2,1-b]pyridine
- 721965-55-5
7-(2-benzyloxy-4-methoxyphenyl)-6-tert-butoxycarbonyl-5-(2,3-dihydrobenzo[b]furan-6-yl)-5-hydroxy-5H-cyclopenta[b]pyridine
Conditions
| Conditions | Yield |
|---|---|
| Stage #1: 6-bromo-2,3-dihydro-1-benzofuran With magnesium In tetrahydrofuran Stage #2: 7-(2-benzyloxy-4-methoxyphenyl)-6-tert-butoxycarbonyl-5-oxocyclopenta-1,3-dieno[2,1-b]pyridine In tetrahydrofuran at -78℃; for 1h; Grignard reaction; | 89% |
- 68-12-2, 33513-42-7
N,N-dimethyl-formamide
- 189035-22-1
6-bromo-2,3-dihydro-1-benzofuran
- 55745-96-5
2,3-dihydro-1-benzofuran-6-carbaldehyde
Conditions
| Conditions | Yield |
|---|---|
| Stage #1: 6-bromo-2,3-dihydro-1-benzofuran With n-butyllithium In 2-methyltetrahydrofuran; hexane at -78℃; for 0.5h; Inert atmosphere; Stage #2: N,N-dimethyl-formamide In 2-methyltetrahydrofuran; hexane at -78℃; for 2h; | 85% |
| Stage #1: 6-bromo-2,3-dihydro-1-benzofuran With n-butyllithium In tetrahydrofuran; hexane at -75℃; for 0.5h; Stage #2: N,N-dimethyl-formamide In tetrahydrofuran; hexane at 20℃; for 0.75h; | 79% |
| Stage #1: 6-bromo-2,3-dihydro-1-benzofuran With n-butyllithium In tetrahydrofuran at -78℃; for 0.5h; Inert atmosphere; Stage #2: N,N-dimethyl-formamide In tetrahydrofuran at -78℃; for 1h; Inert atmosphere; | 52% |
- Total:22 Page 1 of 1 1
Post a RFQ
1
What can I do for you?
Get Best Price
Get Best Price for 189035-22-1
6-BROMO-2,3-DIHYDRO-BENZOFURAN
