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Detail of "19767-45-4"

  • MSDS Download
  • CAS Number:
  • 19767-45-4
  • Name:
  • Mesna

  • Molecular Structure:
  • Formula:
  • C2H5NaO3S2
  • Molecular Weight:
  • 164.18
  • Synonyms:
  • Uromitexan;Sodium 2-mercaptoethanesulfonate;Prestwick_1005;Ethanesulfonic acid,2-mercapto-,monosodium salt;Ethanesulfonic acid, 2-mercapto-, monosodium salt;Mesnaum;Mesna(19767-45-4);2-Mercaptoethanesulfonic Acid Sodium Salt;2-sulfanylethanesulfonic acid;Lomustine,Mesna;
  • EINECS:
  • 243-285-9
  • Melting Point:
  • >240°C dec.
  • Appearance:
  • white to off-white solid
  • Hazard Symbols:
  • IrritantXi
  • Risk Codes:
  • 36/37/38
  • Safety:
  • 26-36 Details

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CAS No.19767-45-4 MesnaCompetitive Product

Assay:99%

Name: Mesna Synonyms: Sodium 2-mercaptoethanesulfonate; Mesnaum; Mesnex Molecular Formula: C2H5NaO3S2 Molecular Weight: 164.17 CAS Registry Number: 19767-45-4

Supplier:Shanghai Chemchallenger Biotech Co., Ltd. [ China (Mainland)]

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CAS No.19767-45-4 MesnaCompetitive Product

Assay:98%

Synonyms: Sodium 2-mercaptoethanesulfonate; Mesnaum; Mesnex Molecular Formula: C2H5NaO3S2 Molecular Weight: 164.17 Risk Codes: R36/37/38 Safety Description: S26;S36 Hazard Symbols: Xi Product Grade Pharmaceutical Grade Pharmacopoeia EP6.0 Capacity 10MT Supply P

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CAS No.19767-45-4 Mesna

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CAS No.19767-45-4 Mesna

Name Mesna Synonyms Sodium 2-mercaptoethanesulfonate; Mesnaum; Mesnex Molecular Structure Molecular Formula C2H5NaO3S2 Molecular Weight 164.17 CAS Registry Number 19767-45-4 EINECS 243-285-9

Supplier:Huei-Ho International Co., Ltd. [ China (Mainland)]

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Chemistry: TOXICITY: SAFETY: Production: Others:

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Assay:98%  Appearance:white to off...  Package:Aluminum foi...  Application:API

Synonyms: Sodium 2-mercaptoethanesulfonate; Mesnaum; Mesnex Molecular Formula: C2H5NaO3S2 Molecular Weight: 164.17 Risk Codes: R36/37/38 Safety Description: S26;S36 Hazard Symbols: Xi Product Grade Pharmaceutical Grade Pharmacopoeia EP6.0

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CAS No.19767-45-4 Mesna

Mesna:is a new sulfur-containing medicine developed in recent years,can prevent the hemorrhagic cystitis and other urinary system epithelial toxicity during the chemotherapy with large dosage of ifosfamide or cyclophosphamide.Serve as protective agent for the urinary track,applie

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  Package:KgStorage:RT  Transportation:normal  Application:APIs

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CAS No.19767-45-4 Mesna

2-Mercaptoethanesulfonic Acid Sodium Salt; MESNA; 2-Mercaptoethanesulphonicacid,sodiumsalt;Mesna; Mesnex; 2-Mercaptoethanesulfonate, sodium; sodium 2-mercaptoethanesulfonate

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CAS No.19767-45-4 Mesna

Synonyms: Sodium 2-mercaptoethanesulfonate; Mesnaum; Mesnex Molecular Formula C2H5NaO3S2 Molecular Weight 164.17 EINECS 243-285-9 Application: It is used in cancer chemotherapy involving cyclophosphamide and ifosfamide as an adjuvant.

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CAS No.19767-45-4 Mesna

Mesna(Uromitexan, Mesnex), a sulfhydryl compound that is used to reduce the incidence of hemorrhagic cystitis associated with certain chemotherapeutic agents.

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CAS No.19767-45-4 Mesna

Chemical name:Sodium 2-mercaptoethanesulphonate Product name:Mesna;Sodium 2-mercaptoethanesulphonate Structural formula:HSCH2CH2SO3Na Molecular formula:C2H5NaO3S2 Molecular weight:164。18 CAS NO. [19767-45-4] Properties:white crystal Quality standard:CP2000 Use:Can be use

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CAS No.19767-45-4 Mesna

Description Mesna belongs to a general group of drugs known as cytoprotective agents. It is used to decrease the risk of bleeding in the bladder due to ifosfamide or high–dose cyclophosphamide. Mesna belongs to a general group of drugs known as cytoprotective agents. It i

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CAS No.19767-45-4 Mesna

Product Name : MESNA Chemical Name : 2-Mercaptoethanesulfonate sodium CAS No : 19767-45-4 Molecular Formula : C2H5NaO3S2 Molecular Weight : 164.181

Supplier:Taiwan Hopax Chemicals Mfg. Co., Ltd [ Taiwan]

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Product name:Mesna

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EP6

Supplier:Jinfan Pharmchem Co., LTD [ China (Mainland)]

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MUCOLYTIC

Supplier:D.K. Pharma Chem Pvt. Ltd. [ India]

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Supplier:Shenzhen Main Luck Pharmaceuticals Inc. [ China (Mainland)]

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Supplier:RA Chem Pharma Limited [ India]

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Supplier:Shanghai win-win biochemical co,.ltd [ China (Mainland)]

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Reference

"Organospecific" detoxification of cytostatic drugs
"Organospecific" detoxification of cytostatic drugs. Brock, Norbert (Degussa Pharma Gruppe, Asta-Werke A.-G., Bielefeld D-4800/14, Fed. Rep. Ger.). Hommage Professeur Rene Truhaut, 152-5. Fac. Pharm. Univ. Paris: Paris, Fr. (French) 1984. CODEN: 55HVAS. DOCUMENT TYPE: Conference; General Review CA Section: 1 (Pharmacology) A review, with 6 refs., of the use of drugs, mainly mesna [19767-45-4], to prevent the toxicity and long-term carcinogenic effects of antitumor drugs in specific organs.
Activation mechanisms of mafosfamide and the role of thiols in cyclophosphamide metabolism
Activation mechanisms of mafosfamide and the role of thiols in cyclophosphamide metabolism. Kwon, Chul Hoon; Borch, Richard F.; Engel, Jurgen; Niemeyer, Ulf (Sch. Med. Dent., Univ. Rochester, Rochester, NY 14642, USA). J. Med. Chem., 30(2), 395-9 (English) 1987.In this article, certain chemicals are used. Some of their cas registry numbers are 35144-64-0 and 56922-83-9 CODEN: JMCMAR. ISSN: 0022-2623. DOCUMENT TYPE: Journal CA Section: 1 (Pharmacology) Section cross-reference(s): 28 cis-Mafosfamide (I) [84210-72-0], a stable analog of cis-4-hydroxycyclophosphamide (II) [61903-29-5], undergoes rapid decompn. in aq. phosphate buffer or plasma at pH 7.4 and 37°. The reaction kinetics of I complex, and trans-mafosfamide (III) [92745-18-1] and II are produced and subsequently disappear over the course of the reaction. The rates of decompn. of I as well as III are much faster in plasma than in buffer. The cis-trans isomerization of I occurs by a specific-base-catalyzed process via iminocyclophosphamide [84489-09-8] as a transient intermediate. In contrast, formation of cis- and trans-mafosmafmide from III and Mesna [19767-45-4] proceeds by an acid-catalyzed process via a hemithioacetal intermediate. The significance of these findings with respect to cyclophosphamide [35144-64-0] metab. is discussed. .
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