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25892-95-9

Basic Information
CAS No.: 25892-95-9
Name: 1-(4-(benzyloxy)-6-hydroxy-2,3-dimethoxyphenyl)ethanone
Article Data: 6
Molecular Structure:
Molecular Structure of 25892-95-9 (1-(4-(benzyloxy)-6-hydroxy-2,3-dimethoxyphenyl)ethanone)
Formula: C17H18O5
Molecular Weight: 302.327
Synonyms: 4-benzyloxy-2,3-dimethoxy-6-hydroxyacetophenone;4-Benzyloxy-2-hydroxy-5,6-dimethoxyacetophenon;2-hydroxy-4-benzyloxy-5,6-dimethoxyacetophenone;1-(4-(BENZYLOXY)-6-HYDROXY-2,3-DIMETHOXYPHENYL)ETHANONE;QC-8452;4-Benzyloxy-2-hydroxy-5,6-dimethoxyacetophenone;I01-8809;
Density: 1.199±0.06 g/cm3(Predicted)
Melting Point: 86–87°C
Boiling Point: 470.1±40.0 °C(Predicted)
PSA: 64.99000
LogP: 3.19100
Synthetic route
25892-94-8

1-(4-(benzyloxy)-3,6-dihydroxy-2-methoxyphenyl)ethan-1-one

77-78-1

dimethyl sulfate

25892-95-9

1-(4-(benzyloxy)-6-hydroxy-2,3-dimethoxyphenyl)ethan-1-one

Conditions
ConditionsYield
With potassium carbonate In acetone at 60℃; for 5h;85%
With potassium carbonate In acetone Heating;59%
In acetone for 5h; Reflux;
90-24-4

2-hydroxy-4,6-dimethoxyacetophenone

25892-95-9

1-(4-(benzyloxy)-6-hydroxy-2,3-dimethoxyphenyl)ethan-1-one

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: 60 percent / aluminium chloride / chlorobenzene / 1 h / Heating
2: 99 percent / K2CO3 / acetone / Heating
3: 29 percent / NaOH; K2S2O8; pyridine / H2O / 24 h / 20 °C
4: 59 percent / K2CO3 / acetone / Heating
View Scheme
480-66-0

2,4,6-trihydroxyacetophenone

25892-95-9

1-(4-(benzyloxy)-6-hydroxy-2,3-dimethoxyphenyl)ethan-1-one

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: 92 percent / K2CO3 / acetone / 3 h / 65 °C
2: 60 percent / aluminium chloride / chlorobenzene / 1 h / Heating
3: 99 percent / K2CO3 / acetone / Heating
4: 29 percent / NaOH; K2S2O8; pyridine / H2O / 24 h / 20 °C
5: 59 percent / K2CO3 / acetone / Heating
View Scheme
3602-54-8

4,6-dihydroxy-2-methoxyacetophenone

25892-95-9

1-(4-(benzyloxy)-6-hydroxy-2,3-dimethoxyphenyl)ethan-1-one

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 99 percent / K2CO3 / acetone / Heating
2: 29 percent / NaOH; K2S2O8; pyridine / H2O / 24 h / 20 °C
3: 59 percent / K2CO3 / acetone / Heating
View Scheme
39548-89-5

1-(4-(benzyloxy)-2-hydroxy-6-methoxyphenyl)ethan-1-one

25892-95-9

1-(4-(benzyloxy)-6-hydroxy-2,3-dimethoxyphenyl)ethan-1-one

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 29 percent / NaOH; K2S2O8; pyridine / H2O / 24 h / 20 °C
2: 59 percent / K2CO3 / acetone / Heating
View Scheme
Multi-step reaction with 2 steps
1: pyridine; dipotassium peroxodisulfate; tetraethylammonium hydroxide / water / 24 h / 20 °C
2: acetone / 5 h / Reflux
View Scheme
Multi-step reaction with 2 steps
1.1: pyridine; tetraethylammonium hydroxide / water / 20 °C
1.2: 24 h / 20 °C
1.3: 1 h / 95 °C
2.1: potassium carbonate / acetone / 5 h / 60 °C
View Scheme
25892-94-8

1-(4-(benzyloxy)-3,6-dihydroxy-2-methoxyphenyl)ethan-1-one

25892-95-9

1-(4-(benzyloxy)-6-hydroxy-2,3-dimethoxyphenyl)ethan-1-one

Conditions
ConditionsYield
In acetone
100-39-0

benzyl bromide

25892-95-9

1-(4-(benzyloxy)-6-hydroxy-2,3-dimethoxyphenyl)ethan-1-one

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: potassium carbonate / acetone / 60 °C
3: potassium hydroxide; pyridine / diethylene glycol; water / 100 °C
4: pyridine; dipotassium peroxodisulfate; tetraethylammonium hydroxide / water / 24 h / 20 °C
5: acetone / 5 h / Reflux
View Scheme
Multi-step reaction with 5 steps
1.1: potassium carbonate / acetone / 5 h / 0 - 60 °C
2.1: potassium hydroxide / acetone / 5 h / 60 °C
3.1: sodium hydroxide; pyridine / water; diethylene glycol / 2 h / 100 °C
4.1: pyridine; tetraethylammonium hydroxide / water / 20 °C
4.2: 24 h / 20 °C
4.3: 1 h / 95 °C
5.1: potassium carbonate / acetone / 5 h / 60 °C
View Scheme
480-40-0

5,7-dihydroxy-2-phenyl-chromen-4-one

25892-95-9

1-(4-(benzyloxy)-6-hydroxy-2,3-dimethoxyphenyl)ethan-1-one

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: potassium carbonate / acetone / 60 °C
3: potassium hydroxide; pyridine / diethylene glycol; water / 100 °C
4: pyridine; dipotassium peroxodisulfate; tetraethylammonium hydroxide / water / 24 h / 20 °C
5: acetone / 5 h / Reflux
View Scheme
Multi-step reaction with 5 steps
1.1: potassium carbonate / acetone / 5 h / 0 - 60 °C
2.1: potassium hydroxide / acetone / 5 h / 60 °C
3.1: sodium hydroxide; pyridine / water; diethylene glycol / 2 h / 100 °C
4.1: pyridine; tetraethylammonium hydroxide / water / 20 °C
4.2: 24 h / 20 °C
4.3: 1 h / 95 °C
5.1: potassium carbonate / acetone / 5 h / 60 °C
View Scheme
110506-85-9

7-(benzyloxy)-5-hydroxy-2-phenyl-4H-chromen-4-one

25892-95-9

1-(4-(benzyloxy)-6-hydroxy-2,3-dimethoxyphenyl)ethan-1-one

Conditions
ConditionsYield
Multi-step reaction with 4 steps
2: potassium hydroxide; pyridine / diethylene glycol; water / 100 °C
3: pyridine; dipotassium peroxodisulfate; tetraethylammonium hydroxide / water / 24 h / 20 °C
4: acetone / 5 h / Reflux
View Scheme
Multi-step reaction with 4 steps
1.1: potassium hydroxide / acetone / 5 h / 60 °C
2.1: sodium hydroxide; pyridine / water; diethylene glycol / 2 h / 100 °C
3.1: pyridine; tetraethylammonium hydroxide / water / 20 °C
3.2: 24 h / 20 °C
3.3: 1 h / 95 °C
4.1: potassium carbonate / acetone / 5 h / 60 °C
View Scheme
681294-57-5

1-(4-(benzyloxy)-2-hydroxy-6-methoxyphenyl)ethanone

25892-95-9

1-(4-(benzyloxy)-6-hydroxy-2,3-dimethoxyphenyl)ethan-1-one

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: potassium hydroxide; pyridine / diethylene glycol; water / 100 °C
2: pyridine; dipotassium peroxodisulfate; tetraethylammonium hydroxide / water / 24 h / 20 °C
3: acetone / 5 h / Reflux
View Scheme
Multi-step reaction with 3 steps
1.1: sodium hydroxide; pyridine / water; diethylene glycol / 2 h / 100 °C
2.1: pyridine; tetraethylammonium hydroxide / water / 20 °C
2.2: 24 h / 20 °C
2.3: 1 h / 95 °C
3.1: potassium carbonate / acetone / 5 h / 60 °C
View Scheme
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  • 1-(4-(benzyloxy)-6-hydroxy-2,3-dimethoxyphenyl)ethanone

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    25892-95-9

    1-(4-(benzyloxy)-6-hydroxy-2,3-dimethoxyphenyl)ethanone

    Min.Order: 0

    FOB Price:  USD $ 0.0-0.0

    1. Production capacity: we have three production base with high-tech production equipment and instruments, equipped with professional production personnel, meet your requirements.2. Quality assurance: we have a first-class testing equipment and testi

    Chemical Technology Co.,LTD is a professional enterprise which engaged in pharmaceutical intermediates, material intermediates production research and development.Company foc

  • Chemical Technology Co.,LTD

     China (Mainland)  |  Contact Details

    Business Type:Other

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  • 1-(4-(benzyloxy)-6-hydroxy-2,3-dimethoxyphenyl)ethanone

  • Casno:

    25892-95-9

    1-(4-(benzyloxy)-6-hydroxy-2,3-dimethoxyphenyl)ethanone

    Min.Order: 0

    FOB Price:  USD $ 0.0-0.0

    Shanghai, Run-Biotech Co., Ltd is a leading domestic pharmaceutical, biopharmaceutical, and health care products R & D outsourcing services company. As an innovation-driven and customer-focused company, Run Biotech provides a broad and integrated por

    Shanghai fine pharma co., Ltd. is a professional enterprise with chemical reagents and fine chemical products development, development and trade. The company has a sound research a

  • Shanghai Run-Biotech Co., Ltd.

     China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:+86-21-31576854/57171705 / 57171706

    Address:second floor, building 3, No.999, jiangyue Road, minghang District, Shanghai, China

       Inquiry Now

  • 1-(4-(benzyloxy)-6-hydroxy-2,3-dimethoxyphenyl)ethanone

  • Casno:

    25892-95-9

    1-(4-(benzyloxy)-6-hydroxy-2,3-dimethoxyphenyl)ethanone

    Min.Order: 0 Metric Ton

    FOB Price:  USD $ 0.0-0.0

    1-(4-(benzyloxy)-6-hydroxy-2,3-dimethoxyphenyl)ethanone Application:1-(4-(benzyloxy)-6-hydroxy-2,3-dimethoxyphenyl)ethanone

    We are a leading global supplier and manufacturer of chiral chemicals, amino acids, aromatic and pyridine halogens, natural extracts and pharmaceutical raw materials. Those chemica

  • tombiopharma

    China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:86--13120615190

    Address:pudong qingmuroad 886# ,shanghai

       Inquiry Now

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