Detail of "30266-58-1"

CAS Number:
30266-58-1
Name:
1,2,3,4-Naphthalenetetrone
Molecular Structure:
Formula:
C₁₀H₄O₄
Molecular Weight:
224.17
Synonyms:
1,2,3,4-Tetraketotetralin;1,2,3,4-Tetraoxo-1,2,3,4-tetrahydronaphthalene;1,2,3,4-Tetraoxotetralin;Oxolin;naphthalene-1,2,3,4-tetrone;naphthalene-1,2,3,4-tetrone;
Density:
1.538 g/cm³
Boiling Point:
394.6 °C at 760 mmHg
Flash Point:
175 °C
Hazard Symbols:
Xi

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Experimental study of ophthalmic drug films with oxolin: Experimental study of ophthalmic drug films with oxolin. Nikolaeva, I. S.; Bogdanova, N. S.; Pershin, G. N.; Kutchak, S. N. (Vses. Nauchno-Issled. Khim.-Farm. Inst. im. Ordzhonikidze, Moscow, USSR). Farmakol. Toksikol. (Moscow), 40(3), 346-8 (Russian) 1977. CODEN: FATOAO. DOCUMENT TYPE: Journal CA Section: 1 (Pharmacodynamics) Polymeric disks each contg. 0.2-0.3 mg oxolin (tetraoxotetrahydronaphthalene dihydrate) [30266-58-1] were effective in treating exptl. herpetic keratitis in rabbits when 1 disk/day was inserted under the lower eyelid.

Distribution of the antiviral preparation oxolin-14C in animals: Distribution of the antiviral preparation oxolin-14C in animals. Ovchinnikov, V. A.; Filatov, P. P.; Chernov, V. A. (Nauchno-Issled. Inst. Med. Radiol., Obninsk, USSR). Khim.-Farm. Zh., 11(9), 24-7 (Russian) 1977. CODEN: KHFZAN. DOCUMENT TYPE: Journal CA Section: 1 (Pharmacodynamics) The radioactivity from 14C-labeled oxolin (I) [30266-58-1] was found in the blood, spleen, kidney, and esp. the liver 15 min after topical application to rat skin. The label was still found in the liver at 48 h post application. Highest levels of label from I-14C administered to rabbit cornea were obsd. 30 min after treatment, esp. in the kidney. Only traces of label were found in organs 48 h after corneal application.