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Detail of "316-81-4"

  • CAS Number:
  • 316-81-4
  • Name:

  • 10H-Phenothiazine-2-sulfonamide,N,N-dimethyl-10-[3-(4-methyl-1-piperazinyl)propyl]-

  • Superlist Name:
  • Thioproperazine
  • Molecular Structure:
  • Formula:
  • C22H30 N4 O2 S2
  • Molecular Weight:
  • 446.68
  • Synonyms:
  • Phenothiazine-2-sulfonamide,N,N-dimethyl-10-[3-(4-methyl-1-piperazinyl)propyl]- (6CI,8CI); 7843RP;Cephalmin;N,N-Dimethyl-10-[3-(4-methyl-1-piperazinyl)propyl]-2-phenothiazinesulfonamide;RP 7843; SKF 5883; Sulfenazin; Thioperazine; Thioproperazine; Tioproperazin
  • EINECS:
  • 206-262-4
  • Density:
  • 1.237g/cm3
  • Melting Point:
  • 140ºC
  • Boiling Point:
  • 612.2°Cat760mmHg
  • Flash Point:
  • 324°C
  • Safety:
  • Moderately toxic by ingestion. Experimental reproductive effects. Human mutation data reported. When heated to decomposition it emits toxic fumes of SOx and NOx. Details
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CAS No.316-81-4 Thioproperazine

Product Nmae： Thioproperazine N,N-Dimethyl-10[3-(4-methyl-1-piperazinyl)propyl]phenothiazine-2-sulfonamide Class： Intermediate products CAS#： 316-81-4 Molecular Formula： C22H30N4O2S2 446.64

Supplier:Changzhou Pailaike Chemicals Co., Ltd. [ China (Mainland)]

119Integral
119

Tel:0519-88371121

Address:NO. 68, qianyang industrial zone, yaoguan town, wujin district, changzhou city, Jiangsu province, China

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Reference

Folin-Ciocalteu reagent as a novel reagent for the detection of phenothiazine drugs
Folin-Ciocalteu reagent as a novel reagent for the detection of phenothiazine drugs. Belal, F. (Fac. Pharm., Mansoura Univ., Mansoura, Egypt). Pharmazie, 38(11), 788 (English) 1983. CODEN: PHARAT. ISSN: 0031-7144. DOCUMENT TYPE: Journal CA Section: 64 (Pharmaceutical Analysis) Phenothiazines, e.g., chlorpromazine [50-53-3], promazine [58-40-2], trifluoperazine [117-89-5], levomepromazine [60-99-1], prochlorperazine [58-38-8], perphenazine [58-39-9], mesoridazine [5588-33-0], acetophenazine [2751-68-0], and thioproperazine [316-81-4], sepd. by silica gel SiO2, all gave a blue color when sprayed with the Folin-Ciocalteu reagent. Oxidn. products of phenothiazines gave no color by this reagent.
Colloidal, partition, and binding properties of phenothiazine derivatives, Part 2
Colloidal, partition, and binding properties of phenothiazine derivatives, Part 2. Effects of chemical structure and environmental conditions on micellar weight. Thoma, Karl; Arning, Manfred (Inst. Galenische Pharm., Johann Wolfgang Goethe-Univ., Frankfurt/Main, Ger.). Arch. Pharm. (Weinheim, Ger.), 309(10), 851-61 (German) 1976. CODEN: ARPMAS. DOCUMENT TYPE: Journal CA Section: 63 (Pharmaceuticals) The micellar wts. of 13 phenothiazine (I) derivs. were detd. in 0.9% NaCl and ranged from 2500 for thioproperazine [316-81-4] (aggregation no. 6) to 25000 for thioridazine [50-52-2] (aggregation no. 67). Substituents on the 2-position of the phenothiazine ring affected both the surface activity and aggregation in the order H
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