Detail of > 50-52-2
- CAS Number:
- 50-52-2
- Name:
10H-Phenothiazine,10-[2-(1-methyl-2-piperidinyl)ethyl]-2-(methylthio)-
- Superlist Name:
- Thioridazine
- Formula:
- C21H26 N2 S2
- Molecular Structure:
![Molecular Structure of 50-52-2 (10H-Phenothiazine,10-[2-(1-methyl-2-piperidinyl)ethyl]-2-(methylthio)-)](http://www.lookchem.com/300w/2010/0621/50-52-2.jpg)
- Synonyms:
- Phenothiazine,10-[2-(1-methyl-2-piperidyl)ethyl]-2-(methylthio)- (6CI,8CI);(?à)-Thioridazine;10-[2-(1-Methyl-2-piperidyl)ethyl]-2-(methylthio)phenothiazine;2-Methylmercapto-10-[2-N-methyl-2-piperidyl)ethyl]phenothiazine;Malloryl;Meleril;Mellaril S;Mellerets;Mellerette;Melleril;Melleril (liquid);Sonapax;TP 21;Thioridazin;Thioridazine;Thioridazine prolongatum;dl-Thioridazine;
- Molecular Weight:
- 370.61
- EINECS:
- 200-044-2
- Safety:
- Human poison by ingestion. Experimental poison by ingestion, subcutaneous, and intraperitoneal routes. Human systemic effects by ingestion: heart rate change, muscle contraction or spasticity, parasympatholytic, toxic psychosis, visual field and retinal changes. Human reproductive effects. Experimental reproductive effects. Mutation data reported. An antipsychotic and sedative. When heated to decomposition it emits very toxic fumes of NOx and SOx.Details
- Deleted CAS:
- 57129-06-3
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Reference
- Quantitative analysis of thioridazine hydrochloride with isothiocyanatochromates
- Quantitative analysis of thioridazine hydrochloride with isothiocyanatochromates. Gaur, Madhu; Saxena, Rashmi; Mathur, P. K.; Kapoor, Subodh N. (Dep. 28511-44-6 and 39697-38-6 are also occured in this study. Chem., Lucknow Univ., Lucknow 226 007, India). Indian Drugs, 21(3), 123-6 (English) 1983. CODEN: INDRBA. ISSN: 0019-462X. DOCUMENT TYPE: Journal CA Section: 64 (Pharmaceutical Analysis) Thioridazine (I) [50-52-2] was detd. in tablets by way of the H2O-insol. complexes formed with Reinecke's salt [13573-16-5], K tetraisothiocyanato diureachromate (III) [28511-44-6], or anilinium tetraisothiocyanatodianilinochromate (III) [39697-38-6]. The complexes can be weighed for gravimetry, digested with 1N KOH, acidified, mixed with ferric alum and AgNO3, and titrated with 0.05N KSCN. The ppts. can be dissolved in Me2CO for measurement of the absorbance at 525 nm. The error was ￡0.68% for gravimetry and ￡1.40% for titrn. .
- Spectrophotometric analysis of thioridazine hydrochloride
- Spectrophotometric analysis of thioridazine hydrochloride. Taha, A. M.; El-Rabbat, N. A.; El-Kommos, M. E.; Refaat, I. H. (Fac. Pharm., Univ. Assiut, Assiut, Egypt). Egypt. J. Pharm. 50-52-2 and 128-08-5 are also in the experiment. Sci., Volume Date 1981, 22(1-4), 163-9 (English) 1983. CODEN: EJPSBZ. ISSN: 0301-5068. DOCUMENT TYPE: Journal CA Section: 64 (Pharmaceutical Analysis) Thioridazine (I) [50-52-2] in tablets is detd. by measuring the absorbance of the violet product formed with N-bromosuccinimide [128-08-5] in 50% H2SO4. At 548 nm, Beer's law held for 9-45 mg/mL. Results agreed with those of the British Pharmacopeia method. .
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