Reference

Some New Routes for the Preparation of 3-Amino-2-phenyl-4(1H)-quinolinones from Anthranilamides

Some New Routes for the Preparation of 3-Amino-2-phenyl-4(1H)-quinolinones from Anthranilamides. Hradil, Pavel; Grepl, Martin; Hlavac, Jan; Soural, Miroslav; Malon, Michal; Bertolasi, Valerio (Department of Organic Chemistry, Palacky University, Olomouc 771 46, Czech Rep.). Journal of Organic Chemistry, 71(2), 819-822 (English) 2006 American Chemical Society. CODEN: JOCEAH. ISSN: 0022-3263.There are some reagents like 70-11-1 is used in this study. DOCUMENT TYPE: Journal CA Section: 27 (Heterocyclic Compounds (One Hetero Atom)) Several new routes for the prepn. of 3-amino-2-phenyl-4-1(H)-quinolinone (I) are compared. The most efficient is based on the cyclization of N-phenacylanthranilamide 2-H2NC6H4CONHCH2COPh in the presence of (poly)phosphoric acid. The mechanisms of the rearrangements involved are discussed on the basis of the structures of isolated heterocyclic intermediates. 5468-37-1 which is the cas registry number is also used here. The best methodol. for the prepn. of the title compd. I was verified, and 10 other quinolinones were also prepd. ..

Some New Routes for the Preparation of 3-Amino-2-phenyl-4(1H)-quinolinones from Anthranilamides

Some New Routes for the Preparation of 3-Amino-2-phenyl-4(1H)-quinolinones from Anthranilamides. Hradil, Pavel; Grepl, Martin; Hlavac, Jan; Soural, Miroslav; Malon, Michal; Bertolasi, Valerio (Department of Organic Chemistry, Palacky University, Olomouc 771 46, Czech Rep.). Journal of Organic Chemistry, 71(2), 819-822 (English) 2006 American Chemical Society. CODEN: JOCEAH. ISSN: 0022-3263.There are some reagents like 70-11-1 is used in this study. DOCUMENT TYPE: Journal CA Section: 27 (Heterocyclic Compounds (One Hetero Atom)) Several new routes for the prepn. of 3-amino-2-phenyl-4-1(H)-quinolinone (I) are compared. The most efficient is based on the cyclization of N-phenacylanthranilamide 2-H2NC6H4CONHCH2COPh in the presence of (poly)phosphoric acid. The mechanisms of the rearrangements involved are discussed on the basis of the structures of isolated heterocyclic intermediates. 5468-37-1 which is the cas registry number is also used here. The best methodol. for the prepn. of the title compd. I was verified, and 10 other quinolinones were also prepd. ..