Reference

Application of high-speed liquid chromatography in phytochemistry

Application of high-speed liquid chromatography in phytochemistry. He, Xian-Guo; Jiang, Fu-Xiang; Zhou, Qian-Ru (Shanghai Inst. Mater. Med., Academia Sinica, Shanghai, Peop. R. China). Chih Wu Hsueh Pao, 20(1), 76-83 (Chinese) 1978. CODEN: CHWHAY. ISSN: 0577-7496. DOCUMENT TYPE: Journal CA Section: 63 (Pharmaceuticals) Section cross-reference(s): 11 The chem. constituents from the fruit and roots of 5 species of Chinese medicinal plants were analyzed by using a high-speed liq. chromatog. system. The major components of Camptotheca acuminata were 10-hydroxycamptothecin [67656-30-8], camptothecin [7689-03-4], 10-methoxycamptothecin [19685-10-0], and vincoside lactam [23141-27-7]. Quercetin [117-39-5], quercitrin [522-12-3], and subgallate [67674-83-3] were the main components of Euphorbia heliascopia Linn. The root exts. from Salvia miltiorhiza Bge. contained mostly tanshinone I [568-73-0], methylene tanshiquinone [67656-29-5], and tanshinone IIA [568-72-9]. The major constituents from fruits of Schisandra sphenanthera Rehd. et Wils. were schisantherin A [58546-56-8],B [58546-55-7], and C [64938-51-8]. The root exts. from Daphne genkwa Sieb et Zucc. consisted mostly of yuanhuacin [66673-22-1]. The packings for liq. chromatog. as well as the therapeutic effects of these chem. compds. are discussed.

The antibacterial components of Dan-Shen

The antibacterial components of Dan-Shen. Fang, Chi-Nien; Chang, Pei-Ling; Hsu, Tsong-Pei (Inst. Mater. Med., Chin. Acad. Med. Sci., Peking, Peop. R. China). Hua Hsueh Hsueh Pao, 34(3), 197-209 (Chinese) 1976. CODEN: HHHPA4. ISSN: 0567-7351. DOCUMENT TYPE: Journal CA Section: 63 (Pharmaceuticals) Section cross-reference(s): 11, 3 Roots of Salvia miltiorrhiza (Dan-Shen) were extd. with ether, and the ext. was treated with 5% Na2CO3 to give a neutral fraction and a Na2CO3 fraction, followed by silica gel column chromatog. and thin-layer chromatog. The components sepd. were identified by UV, IR, and NMR spectrometry. Tanshinone I [568-73-0], tanshinone IIA [568-72-9], cryptotanshinone [35825-57-1], Me tanshinate [18887-19-9], hydroxytanshinone IIA [18887-18-8], tanshinone IIB [17397-93-2] and dihydrotanshinone I [20958-19-4] were detected in the neutral fraction, and 3 new compds. [danshexinkun A (I) [65907-75-7], danshexinkun B (II) [65907-76-8] and danshexinkun C (III) [65907-77-9]] were identified in the Na2CO3 fraction. Cryptotanshinone, dihydrotanshinone I, hydroxytanshinone IIA, Me tanshinate, and tanshinone IIB showed strong inhibitory activities against Staphylococcus aureus in vitro. Pharmaceutical prepns. contg. the compds. as active ingredients have been clin. applied.