CAS No.591-97-9,2-Butene, 1-chloro- Suppliers,MSDS download

Detail of "591-97-9"

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CAS Number:

591-97-9

Name:

2-Butene, 1-chloro-

Superlist Name:

1-Chloro-2-butene

Molecular Structure:

Formula:

C₄H₇Cl

Molecular Weight:

90.55

Synonyms:

1-Chloro-2-butene;2-Buten-1-yl chloride;2-Butenyl chloride;Crotyl chloride;a-Chloro-b-butylene;g-Methallyl chloride;g-Methylallyl chloride;

EINECS:

209-739-5

Density:

0.909 g/cm³

Melting Point:

-65 °C

Boiling Point:

84.5 °C at 760 mmHg

Appearance:

colourless liquid

Hazard Symbols:

Risk Codes:

11-22-34

Safety:

16-26-36/37/39-45 Details

Transport Information:

UN 2924 3/PG 2

Reference

Induction of unscheduled DNA synthesis in HeLa cells by allylic compounds: Induction of unscheduled DNA synthesis in HeLa cells by allylic compounds. Schiffmann, Dietmar; Eder, Erwin; Neudecker, Tilman; Henschler, Dietrich (Inst. Toxicol.In this study， 115-07-1 and 10061-02-6 are also used., Univ. Wuerzburg, Wuerzburg D-8700, Fed. Rep. Ger.). Cancer Lett. (Shannon, Irel.), 20(3), 263-9 (English) 1983. CODEN: CALEDQ. ISSN: 0304-3835. DOCUMENT TYPE: Journal CA Section: 4 (Toxicology) Thirteen allylic compds., mostly with close structural relation, were tested for their ability to induce unscheduled DNA synthesis (UDS) in HeLa cells and mutations in the Ames test; 11 induced UDS dose dependently. Allyl isothiocyanate [57-06-7] was neg. in UDS (borderline in the Ames test) and acrolein [107-02-8] (pos. in the Ames test) proved toxic to HeLa cells; thus, UDS measurement was excluded. In general, pos. qual. and quant. correlation between UDS, Ames test, and alkylating properties (as measured in the 4-nitrobenzylpyridine test) were found. Among structural analogs and typical allylic compds. with various leaving groups, the amt. of induced DNA repair at equimolar concns. decreased in the same order as the mutagenic and alkylating activities in the other 2 test systems: cis-1,3-dichloropropene [10061-01-5] > trans-1,3-dichloropropene [10061-02-6] > 2,3,-dichloro-1-propene [78-88-6]; 1-chloro-2-butene [591-97-9] > 3-chloro-1-butene [563-52-0] > 3-chloro-2-methyl-1-propene [563-47-3] > allyl chloride [107-05-1]; allyl methanesulfonate [6728-21-8] > allyl iodide [556-56-9] > allyl bromide [106-95-6] > allyl chloride. .

Labeled compounds of potential biological interest: Labeled compounds of potential biological interest. III. Tritium labeling of 1-butyl-3-piperidyl 2-methyl-6-chloro-carbanilate with high specific activity. Gosztonyi, Tamas; Sandberg, Rune; Ramsay, Carl H. (Res. Dev. Lab., Astra Laekemedel AB, Soedertaelje, Swed.). J. Labelled Compd. Radiopharm., 12(3), 477-80 (English) 1976. 591-97-9 and 33531-28-1 are also in the experiment. CODEN: JLCRD4. DOCUMENT TYPE: Journal CA Section: 27 (Heterocyclic Compounds (One Hetero Atom)) Section cross-reference(s): 1 1-(2-Butenyl)-3-piperidinol, prepd. by reaction of 3-piperidinol with MeCH:CHCH2Cl, was coupled with 2,6-MeClC6H3NCO to give the carbanilate I which was hydrogenated with T gas over Pd/C to give the title compd. T labeled with sp. activity 20.1 Ci/mmole. .

Detail of "591-97-9"

2-Butene, 1-chloro-

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CAS No.591-97-9 1-Chloro-2-butene

CAS No.591-97-9 1-Chloro-2-butene

CAS No.591-97-9 1-Chloro-2-butene

CAS No.591-97-9 1-Chloro-2-butene

CAS No.591-97-9 1-Chloro-2-butene

CAS No.591-97-9 1-Chloro-2-butene

CAS No.591-97-9 1-Chloro-2-butene

CAS No.591-97-9 1-Chloro-2-butene

CAS No.591-97-9 1-Chloro-2-butene

CAS No.591-97-9 1-Chloro-2-butene

CAS No.591-97-9 1-Chloro-2-butene

CAS No.591-97-9 1-Chloro-2-butene

CAS No.591-97-9 1-Chloro-2-butene

Reference