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Detail of "60-92-4"

  • MSDS Download
  • CAS Number:
  • 60-92-4
  • Name:
  • Cyclic AMP

  • Molecular Structure:
  • Formula:
  • C10H12N5O6P
  • Molecular Weight:
  • 329.24
  • Synonyms:
  • 3',5'-AMP;AMPc;Adenosine 3',5'-cyclophosphate;Adenosine 3',5'-monophosphate;Adenosine 3',5'-phosphate;Adenosine cyclic 3',5'-monophosphate;Adenosine cyclic monophosphate;Cyclic 3',5'-AMP;Cyclic3',5'-adenylic acid;Cyclic adenosine 3',5'-monophosphate;Cyclicadenosine 3',5'-phosphate;NSC 143670;NSC 94017;cAMP;
  • EINECS:
  • 200-492-9
  • Density:
  • 2.47 g/cm3
  • Melting Point:
  • 260 °C (dec.)(lit.)
  • Boiling Point:
  • 701.5 °C at 760 mmHg
  • Flash Point:
  • 378 °C
  • Solubility:
  • 50 mg/mL in water
  • Appearance:
  • white crystalline powder
  • Hazard Symbols:
  • CorrosiveC, IrritantXi
  • Risk Codes:
  • 34-36/37/38
  • Safety:
  • 22-24/25-45-36/37/39-26-36 Details

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CAS No.60-92-4 Cyclic AMPCompetitive Product

Assay:98%  Appearance:white or alm...  Package:Packing:1Kg/...

Product Name: Adenosine Cyclophosphate CAS#: 60-92-4 Appearance : white or almost white crystal powder Standard: Assay:98% Packing:1Kg/can

Supplier:Henan Legend Wealth Trading and Industrial Co.,Ltd. [ China (Mainland)]

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CAS No.60-92-4 Cyclic AMP

C10H11N5O6P 328.1986 InChI=1/C10H12N5O6P/c11-8-5-9(13-2-12-8)15(3-14-5)10-6(16)7-4(20-10)1-19-22(17,18)21-7/h2-4,6-7,10,16H,1H2,(H,17,18)(H2,11,12,13)/p-1/t4-,6-,7-,10-/m1/s1

Supplier:TIANJIN COOKMAN CHEMICAL IMP & EXP CO.,LTD. [ China (Mainland)]

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CAS No.60-92-4 Cyclic AMP

Product description : It is an important second messenger. It forms, as shown, when the membrane enzyme adenylyl cyclase is activated.The cyclic AMP then goes on the activate specific proteins. Some ion channels, for example, are gated by cyclic AMP. But an especially important

Supplier:Tianjin Chicheng Chemicals Co.,ltd. [ China (Mainland)]

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CAS No.60-92-4 Cyclic AMP

C10H11N5O6P 328.1986 InChI=1/C10H12N5O6P/c11-8-5-9(13-2-12-8)15(3-14-5)10-6(16)7-4(20-10)1-19-22(17,18)21-7/h2-4,6-7,10,16H,1H2,(H,17,18)(H2,11,12,13)/p-1/t4-,6-,7-,10-/m1/s1

Supplier:Tianjin Yaoyu Chemicals co.,ltd [ China (Mainland)]

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1520Integral
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CAS No.60-92-4 Cyclic AMP

60-92-4

Supplier:TCS INDUSTRY LIMITED [ China (Mainland)]

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CAS No.60-92-4 Cyclic AMP

Assay:98%

Supplier:Hangzhou Dayangchem Co., Ltd. [ China (Mainland)]

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CAS No.60-92-4 Cyclic AMP

Nucleotides

Supplier:Trademax Pharmaceuticals & Chemicals Co., Ltd [ China (Mainland)]

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CAS No.60-92-4 Cyclic AMP

Adenosine-3',5'-cyclic monophosphate

Supplier:CHEMIMPEX INT'L INC [ United States]

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CAS No.60-92-4 Cyclic AMP

Supplier:Changzhou Carbochem Co.,Ltd [ China (Mainland)]

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CAS No.60-92-4 Cyclic AMP

Assay:98%

Supplier:shanghai jinshan pharmaceutical Co.,Ltd [ China (Mainland)]

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Manufacturer 2610Integral
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CAS No.60-92-4 Cyclic AMP

Supplier:Shanghai Majin Pharmaceutical & Chemical Technology Co. Ltd [ China (Mainland)]

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CAS No.60-92-4 Cyclic AMP

Assay:99%  Appearance:white or off...

Supplier:Hangzhou meiya pharmaceutical co.,ltd [ China (Mainland)]

Manufacturer 581Integral
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CAS No.60-92-4 Cyclic AMP

Supplier:Upstate [ United States]

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CAS No.60-92-4 Cyclic AMP

Supplier:AXXORA, LLC [ Switzerland]

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CAS No.60-92-4 Cyclic AMP

Supplier:Sisco Research Laboratories [ India]

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CAS No.60-92-4 Cyclic AMP

Supplier:Pfaltz & Bauer, Inc. [ United States]

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CAS No.60-92-4 Cyclic AMP

Supplier:ADVANCED TECH. & IND. CO., LTD. [ Hong Kong]

610Integral
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CAS No.60-92-4 Cyclic AMP

Supplier:BIOLOG [ Germany]

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Reference

Effects of castration and sex steroids on the thyroid response to thyrotropin
Effects of castration and sex steroids on the thyroid response to thyrotropin. Bagchi, N.; Shivers, B.; Brown, T. R. (Dep. Med., Wayne State Univ., Detroit, MI 48201, USA). Endocrinology (Baltimore), 114(5), 1652-6 (English) 1984. CODEN: ENDOAO. ISSN: 0013-7227. DOCUMENT TYPE: Journal CA Section: 2 (Mammalian Hormones) The possibility of a direct effect of sex steroids on the thyroid gland was studied by investigating thyroid function in castrated mice. The basal rates of thyroglobulin hydrolysis were similar in intact and castrated mice, but TSH [9002-71-5]-stimulated rates were higher in both male and female castrates. Daily treatment of castrates for a week with 17b-estradiol [50-28-2] or testosterone [58-22-0] decreased the rate of thyroglobulin hydrolysis to that seen in intact mice, but dihydrotestosterone [521-18-6] was without effect. Dibutyryl cAMP [362-74-3] added in vitro increased the rate of thyroglobulin hydrolysis in both intact and castrated mice, but the stimulation was greater in the castrates. Basal and TSH-stimulated cAMP [60-92-4] levels in the thyroid were similar in castrated and intact mice. There was no difference in thyroidal incorporation of I by intact and castrated mice in either the presence or absence of TSH. Castration apparently results in greater sensitivity to TSH with respect to thyroid hormone secretion. Thyroid hormone synthesis, basal or TSH-stimulated, is, however, unaltered. Estradiol inhibits TSH-stimulated hormone release in castrates. Testosterone has a similar effect, possibly through aromatization to estradiol. The effect of sex hormones is likely to be exerted at a post-cAMP step specific for hormone secretion.
Increased release of cyclic adenosine monophosphate into jugular vein in response to isoproterenol administration
Increased release of cyclic adenosine monophosphate into jugular vein in response to isoproterenol administration. Altszuler, Norman; Friedman, Eitan; Laschinger, John C.; Catinella, Frank P.; Cunningham, Joseph N., Jr.; Nathan, Ira M. (Sch. Med., New York Univ., New York, NY 10016, USA). Life Sci., 35(9), 963-7 (English) 1984. CODEN: LIFSAK. ISSN: 0024-3205. DOCUMENT TYPE: Journal CA Section: 1 (Pharmacology) Section cross-reference(s): 2 Catecholamine administration elevates plasma cAMP [60-92-4] levels but the source of the cAMP is unknown. To det. possible sources, plasma cAMP levels were detd. in blood vessels across the head, liver, kidneys and lungs in anesthetized dogs infused with the b-adrenergic agonist isoproterenol [7683-59-2]. Only the head gave an increased release of cAMP into the blood. The kidneys removed cAMP from the blood, while the liver and lungs showed no change. This in vivo release of cAMP from the head represents contributions from brain and facial muscles and may be a useful approach to study brain involvement in the action of various hormones and drugs.
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