Products Categories
CAS No.: | 630-25-1 |
---|---|
Name: | 1,2-Dibromotetrachloroethane |
Article Data: | 12 |
Molecular Structure: | |
Formula: | C2Br2Cl4 |
Molecular Weight: | 325.642 |
Synonyms: | 1,2-dibromo-1,1,2,2-tetrachloro-ethan;Dbtce;Ethane, 1,2-dibromo-1,1,2,2-tetrachloro-;Ethane, 1,2-dibromo-tetrachloro-;ethane,1,2-dibromo-1,1,2,2-tetrachloro-;sym-Dibromotetrachloroethane;1,1,2,2-TETRACHLORODIBROMOETHANE;1,2-DIBROMOTETRACHLOROETHANE |
EINECS: | 211-136-7 |
Density: | 2.438 g/cm3 |
Melting Point: | 215-220 °C (dec.)(lit.) |
Boiling Point: | 219 °C at 760 mmHg |
Flash Point: | 104.9 °C |
Solubility: | Insoluble in water. |
Appearance: | colourless solid |
Hazard Symbols: | Xi |
Risk Codes: | 36/37/38 |
Safety: | 26-37/39 |
PSA: | 0.00000 |
LogP: | 4.03900 |
Conditions | Yield |
---|---|
With bromine for 2h; Irradiation; | 94% |
With bromine In dichloromethane for 72h; Heating; | 85% |
With bromine photochemische Bildung; | |
With bromine Geschwindigkeit der Bildung; |
Conditions | Yield |
---|---|
With aluminium trichloride; bromine at 70℃; |
1,2-dibromo-1,1,2,2-tetrachloroethane
Conditions | Yield |
---|---|
With bromine im Sonnenlicht; |
dibromodichloromethane
A
tetrachloromethane
B
1,1,2,2-tetrachloroethylene
C
1,2-dibromo-1,1,2,2-tetrachloroethane
D
Bromotrichloromethane
E
bromine
Conditions | Yield |
---|---|
In neat (no solvent) Kinetics; other Radiation; γ-radiolysis at -196 and 131°C;; |
[(bis(1-methylethyl)amino)carbonyl]ferrocene
1,2-dibromo-1,1,2,2-tetrachloroethane
(pR)-2-bromo-(N,N-diisopropyl)ferrocenecarboxamide
Conditions | Yield |
---|---|
With (-)-sparteine; n-butyllithium In diethyl ether under Ar atm. to soln. (-)-sparteine in Et2O at -78°C n-BuLi was added over 30 min, stirred for 1.5 h, soln. BrCCl2CCl2Br in Et2O was added over 20 min, stirred for 1 h and allowed to warm to room temp.; react. mixt. was quenched with aq. NH4Cl, extd. with Et2O, washed with water and brine, dried, filtered, and evapd., chromy. on silica (hexane-EtOAc 9:1); elem. anal.; | 99% |
1,2-dibromo-1,1,2,2-tetrachloroethane
Conditions | Yield |
---|---|
In dichloromethane at 20℃; for 0.5h; Inert atmosphere; | 98% |
1,2-dibromo-1,1,2,2-tetrachloroethane
Conditions | Yield |
---|---|
Stage #1: 4,4',5,5'-tetrahydro-7,7'-spirobi[thieno[2,3-c]pyran] With n-butyllithium In tetrahydrofuran; hexane at -78℃; for 1h; Schlenk technique; Inert atmosphere; Stage #2: 1,2-dibromo-1,1,2,2-tetrachloroethane In tetrahydrofuran; hexane at -78 - 20℃; Schlenk technique; Inert atmosphere; | 96% |
N-(2-fluoro-5-pyridyl)cyclopropane carboxamide
1,2-dibromo-1,1,2,2-tetrachloroethane
Conditions | Yield |
---|---|
With triethylamine; triphenylphosphine In 1,2-dichloro-ethane | 95% |
Conditions | Yield |
---|---|
With potassium tert-butoxide; t-butyl lithium In tetrahydrofuran; hexane Schlenk techniques used under N2 or Ar, THF soln. of FcH (10.8 mmol) andtBuOK(1.34 mmol) cooled to -78°C, after >15 min tBuLi soln.(21.6 mmol) dropwise added, stirred for 1.5 h at <-70°C, C2Cl4Br2 adde d, stirred for 30 min at -78°C; allowed to warm to room temp., quenched with H2O, extracted with CH2Cl2,organic layer washed with H2O, dried over MgSO4, solvent removed under vac., chromd. (neutral alumina, hexane); NMR; | 95% |
Stage #1: ferrocene With potassium tert-butylate; tert.-butyl lithium In tetrahydrofuran at -78℃; for 2h; Inert atmosphere; Stage #2: 1,2-dibromo-1,1,2,2-tetrachloroethane In tetrahydrofuran at -78℃; for 0.5h; Inert atmosphere; | 88% |
Stage #1: ferrocene With potassium tert-butylate; tert.-butyl lithium In tetrahydrofuran; hexane at -78℃; for 1.5h; Stage #2: 1,2-dibromo-1,1,2,2-tetrachloroethane In tetrahydrofuran; hexane at -78℃; for 0.5h; | 80% |
1,2-dibromo-1,1,2,2-tetrachloroethane
Conditions | Yield |
---|---|
Stage #1: 4,4',5,5'-tetrahydro-7,7'-spirobi[thieno[2,3-c]pyran] With n-butyllithium In tetrahydrofuran; hexane at -78℃; for 1h; Schlenk technique; Inert atmosphere; Stage #2: 1,2-dibromo-1,1,2,2-tetrachloroethane In tetrahydrofuran; hexane at -78 - 20℃; Schlenk technique; Inert atmosphere; | 95% |
What can I do for you?
Get Best Price
The Ethane,1,2-dibromo-1,1,2,2-tetrachloro-, belongs to the following product categories: (1)Ethanes/ethenes; (2)Bromination; (3)Halogenation; (4)Synthetic Organic Chemistry; (5)Alkyl; (6)Halogenated Hydrocarbons; (7)Organic Building Blocks. It has the systematic name of 1,2-dibromo-1,1,2,2-tetrachloroethane. And this chemical is a kind of colourless solid.
Physical properties of Ethane,1,2-dibromo-1,1,2,2-tetrachloro-: (1)ACD/LogP: 5.39; (2)# of Rule of 5 Violations: 1; (3)ACD/LogD (pH 5.5): 5.38; (4)ACD/LogD (pH 7.4): 5.38; (5)ACD/BCF (pH 5.5): 7285.56; (6)ACD/BCF (pH 7.4): 7285.56; (7)ACD/KOC (pH 5.5): 20246.13; (8)ACD/KOC (pH 7.4): 20246.13; (9)#H bond acceptors: 0; (10)#H bond donors: 0; (11)#Freely Rotating Bonds: 1; (12)Polar Surface Area: 0 Å2; (13)Index of Refraction: 1.606; (14)Molar Refractivity: 46.1 cm3; (15)Molar Volume: 133.5 cm3; (16)Polarizability: 18.27×10-24cm3; (17)Surface Tension: 52.7 dyne/cm; (18)Enthalpy of Vaporization: 43.68 kJ/mol; (19)Vapour Pressure: 0.18 mmHg at 25°C.
Uses of Ethane,1,2-dibromo-1,1,2,2-tetrachloro-: it can be used to produce 1,1,2,2-tetrachloro-1,2-difluoro-ethane. This reaction will need reagent ClF and solvent 1,1,2-trichloro-1,2,2-trifluoro-ethane. The yield is about 80%.
You can still convert the following datas into molecular structure:
(1)SMILES: BrC(Cl)(Cl)C(Br)(Cl)Cl
(2)InChI: InChI=1/C2Br2Cl4/c3-1(5,6)2(4,7)8
(3)InChIKey: WJUKOGPNGRUXMG-UHFFFAOYAQ
(4)Std. InChI: InChI=1S/C2Br2Cl4/c3-1(5,6)2(4,7)8
(5)Std. InChIKey: WJUKOGPNGRUXMG-UHFFFAOYSA-N
The toxicity data is as follows:
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
rat | LD | oral | > 500mg/kg (500mg/kg) | National Academy of Sciences, National Research Council, Chemical-Biological Coordination Center, Review. Vol. 5, Pg. 18, 1953. |