Detail of > 69-81-8
- CAS Number:
- 69-81-8
- Name:
Hydrazinecarboxamide,2-(1,2,3,6-tetrahydro-3-hydroxy-1-methyl-6-oxo-5H-indol-5-ylidene)-
- Superlist Name:
- Carbazochrome
- Formula:
- C10H12N4O3
- Molecular Structure:

- Synonyms:
- Cromadrenal;Cromosil;NSC 73742;Sangostasin;Sangostazin;5,6-Indolinedione,3-hydroxy-1-methyl-, 5-semicarbazone (7CI,8CI);Adrenochrome semicarbazone(6CI);3-Hydroxy-1-methyl-5,6-indolindione 5-semicarbazone;Adchnon;Adedolon;Adrenochrome monosemicarbazone;Adrenostazin;Adrenoxyl;Adrezon;Adrokson;Adroxon;Cartabes;
- Molecular Weight:
- 236.2273
- EINECS:
- 200-717-0
- Density:
- 1.63 g/cm3
- Appearance:
- nacarat crystalline powder
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Reference
- Studies on the incompatibility of the parenteral solution
- Studies on the incompatibility of the parenteral solution. VIII. Incompatibility of two kinds of carbazochrome preparations. Koshiro, Akira; Katsuno, Atsushi; Ogawa, Toyoko; Yonekawa, Chiyo; Hironaga, Chikako; Toyota, Keiko; Kato, Yasufumi; Chida, Hiromitsu; Ogata, Tetsuya; et al. (Yamaguchi Univ. Hosp., Yamaguchi, Japan). Kyushu Yakugakkai Kaiho, 31, 63-70 (Japanese) 1977. CODEN: KYYKBN. ISSN: 0368-7279. DOCUMENT TYPE: Journal CA Section: 63 (Pharmaceuticals) Incompatibility of carbazochrome (I) [69-81-8] and I sulfonate [51460-26-5] injections was tested with 96 parenteral solns. Levomepromazine-HCl [1236-99-3] and prochloroperazine methansulfonate [3111-70-4] were incompatible with both the I prepns., and tetracycline-HCl [64-75-5] and pentazocine lactate [17146-95-1] were incompatible with only I prepn. as seen by the turbidity of the mixts. and crystal formation. These changes resulted from the formation of the insol. free base of the additives and were assocd. with pH changes.
- Dentifrices containing carbazochromes for gingival inflammation and bleeding control
- Dentifrices containing carbazochromes for gingival inflammation and bleeding control. (Lion Corp., Japan). Jpn. Kokai Tokkyo Koho JP 59227812 A2 21 Dec 1984 Showa, 7 pp. (Japanese). (Japan). CODEN: JKXXAF. CLASS: ICM: A61K007-26. APPLICATION: JP 83-101464 7 Jun 1983. DOCUMENT TYPE: Patent CA Section: 62 (Essential Oils and Cosmetics) Section cross-reference(s): 1, 63 Dentifrices effective in controlling gingivitis and gingival bleeding contain carbazochrome (I) [69-81-8], its derivs. and one or more components selected from glycyrrhetinic acid, its salts, and coca exts. Thus, a mouthwash comprises 95% glycerin 20, 60% sorbitol 20, Carbopol 0.001, polyoxyethylene sorbitan monolaurate 1.0, polyoxyethylene stearate 1.0, Na saccharin 0.1, flavoring 1.0, tranexamic acid [1197-18-8] 0.05, coca MeOH ext. 0.05, carbazochrome 0.1, and H2O to 100% by wt.
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