Reference

Direct obtention of pure compounds from crude plant extracts by preparative liquid chromatography

Direct obtention of pure compounds from crude plant extracts by preparative liquid chromatography. Hostettmann, Kurt; Pettei, Michael J.; Kubo, Isao; Nakanishi, Koji (Dep. Chem., Columbia Univ., New York, N. Y., USA). Helv. Chim. Acta, 60(2), 670-2 (English) 1977. CODEN: HCACAV. DOCUMENT TYPE: Journal CA Section: 63 (Pharmaceuticals) Fagara chalybea bark was estd. with hexane, the polar function was removed by column chromatog. on silica gel using 1:1 ether-hexane as solvent, and the polar fraction was sepd. into 6 fractions by preparative chromatog. using solvents with increasing polarity. Four of the fractions were pure compds., 3 of which were identified as germacrone (I) [6902-91-6], dihydrochelerythrine (II) [6880-91-7], and N-methylflindersine (III) [50333-13-6], a new alkaloid, by spectroscopic methods. The entire sepn. process required 2-3 h compared to .apprx.2-3 weeks by conventional chromatog.

GC-MS analysis of essential oil of Rhododendron dauricum L

GC-MS analysis of essential oil of Rhododendron dauricum L. Ma, Yaping; Sun, Shouwei; Wu, Chengshun (Natl. Inst. Metrol., Peop. Rep. China). Zhiwu Xuebao, 25(6), 563-7 (Chinese) 1983. CODEN: CHWHAY. ISSN: 0577-7496. DOCUMENT TYPE: Journal CA Section: 62 (Essential Oils and Cosmetics) Section cross-reference(s): 11, 63 R. dauricum (A medicinal plant) leaf oil contained a-pinene [80-56-8], camphene [79-92-5], b-pinene [127-91-3], limonene [138-86-3], cyclofenchene [488-97-1], 1-methyl-2-isopropylbenzene [527-84-4], 3-methylbutyl isovalerate [659-70-1], a-copaene [3856-25-5], (1a,3aa,3ba,6ab,6ba)-decahydro-3a-methyl-6-methylene-1-(1-meth ylethyl)cyclobuta[1,2:3,4]dicyclopentane [5208-59-3], bornyl acetate [76-49-3], cis-4,11,11-trimethyl-8-methylenebicyclo[7.2. 3856-25-5 and 10208-80-7 which are cas registry numbers of chemicals are mentioned.0]undec-4-ene [89575-63-3], d-guaiene [3691-11-0], g-muurolene [30021-74-0], b-maaliene [489-29-2], eremophilone [562-23-2], a-muurolene [10208-80-7], d-cadinene [483-76-1], g-cadinene [39029-41-9], g-selinene [515-17-3], 4,10-dimethyl-7-isopropylbicyclo[4.4.0]-1,4-decadiene [16728-99-7], g-elemene [29873-99-2], germacrone [6902-91-6], juniper camphor [473-04-1] and b-selinene [17066-67-0] as detd. by gas chromatog.-mass spectroscopy (GC-MS). .