Detail of "831-81-2"

Reference

New metabolites of hydroxyzine in a human urine

New metabolites of hydroxyzine in a human urine. Kageura, Mitsuyoshi; Kataoka, Mutsumi; Nagata, Takeaki; Hara, Kenji (Sch. Med., Fukuoka Univ., Japan). Iyo Masu Kenkyukai Koenshu, 9, 273-6 (Japanese) 1984. CODEN: KIMKDN. DOCUMENT TYPE: Journal CA Section: 4 (Toxicology) Metabolites of hydroxyzine (I) [68-88-2] in urine of a male subject who attempted suicide by introducing exhaust gas into his car after drinking sake and taking I were detd. by gas chromatog.-mass spectroscopy. The metabolites were identified as 4-chlorodiphenylmethane (II) [831-81-2], p-chlorbenzophenone [134-85-0], norchlorcyclizine [303-26-4], III [95088-21-4], IV [95088-22-5], V [95088-23-6], and VI [95088-24-7]. II, III, IV, V and VI have not been reported previously.

Changed compounds of hydroxyzine in a human urine

Changed compounds of hydroxyzine in a human urine. Kageura, M.; Kataoka, M.; Hara, K.; Nagata, T. (Sch. Med., Fukuoka Univ., Fukuoka 814-01, Japan). Forensic Sci. Int., 32(4), 229-35 (English) 1986. CODEN: FSINDR. ISSN: 0379-0738. DOCUMENT TYPE: Journal CA Section: 4 (Toxicology) Section cross-reference(s): 1 During a forensic toxicol. gas chromatog. 303-26-4 and 95088-24-7 which are cas registry numbers of chemicals are mentioned./mass spectrometry screening, changed compds. of hydroxyzine (I) [68-88-2] were found in a man's urine taken ~20 h after ingesting sake (Japanese liquor) and tranquilizers. The structures of those compds. were assigned to 4-chlorodiphenylmethane (II) [831-81-2], p-chlorbenzophenone (III) [134-85-0], norchlorcyclizine (IV) [303-26-4], 7-(p-chloro-a-phenylbenzyl)-2-hydroxy-2H,3H-oxazolo-[3,2-a]piperazi ne (V) [95088-21-4], 1-(p-chloro-a-phenylbenzyl)-4-methylpiperazine-3-one (VI) [95088-22-5], N-(p-chloro-a-phenylbenzyl)-N-formylmethyl-N'-hydroxyethyl-1,2-eth enediamine (VII) [95088-23-6] and 1-(p-chloro-a-phenylbenzyl)-4-[2-ethoxy(2-ethoxy)ethyl]piperazine (VIII) [95088-24-7] on the basis of the fragmentation patterns and relative retention times except VIII which was identified using the synthesized compd. II, V, VI, VII, and VIII have not been reported previously, but the possibility of metabolites of hydroxyzine is still uncertain. .