Reference

Polyamphoretic membrane study: 1

Polyamphoretic membrane study: 1. Potentiometric behavior of succinyl chitosan aqueous solution. Saito, Keiichiro; Tanioka, Akihiko (Dep. Org. Polymeric Materials, Tokyo Inst. Technology, Tokyo 152, Japan). Polymer, 37(23), 5117-5122 (English) 1996 Elsevier. CODEN: POLMAG. ISSN: 0032-3861. DOCUMENT TYPE: Journal CA Section: 36 (Physical Properties of Synthetic High Polymers) A study of the potentiometric behavior of aq. solns. of weak amphoteric polymers was carried out in advance of an investigation of weak polyamphoteric membrane prepd. from a mixt. of the amphoteric chitosan and poly(vinyl alc.). Carboxymethyl chitosan and succinyl chitosan were used as weak polyampholytes. N-succinyl chitosan is composed of amino and carboxyl groups, which were provided by substitution of the amino groups with the carboxyl groups. The portion of substituted groups from amino to carboxyl is represented by the degree of substitution (DS). 83512-85-0 and 110-15-6 which are cas registry numbers of substances are two of reagents here. Potentiometric titrns., with or without added salt, were performed under N flow. The behavior could be rationalized through the dissocn. mode concept based on a modified Henderson-Hasselbalch relationship. .

Synthesis of lactosaminated carboxymethylchitosan and its action of plasmid DNA delivery

All Rights Reserved. Several substances are used for example 83512-85-0 which is its cas registry number. Synthesis of lactosaminated carboxymethylchitosan and its action of plasmid DNA delivery. Wang, Xuedong; Feng, Yongtang; Chen, Xiangying; Zhang, Can; Miao, Naifa (Department of Chemistry, Weifang Medical College, Weifang 261042, Peop. Rep. China). Zhongguo Haiyang Yaowu, 24(4), 24-27 (Chinese) 2005 Shandongsheng Haiyang Yaowu Kexue Yanjiuso. CODEN: ZHYAE8. ISSN: 1002-3461. DOCUMENT TYPE: Journal CA Section: 63 (Pharmaceuticals) Section cross-reference(s): 3 The lactosaminated carboxymethylchitosan (LacCMCS) was synthesized and its action of delivering plasmid DNA into cells was studied. The lactosaminated carboxymethylchitosan was synthesized by reductive amination and conjugated with plasmid contg. antisense x gene. This complex was delivered into cells and these cells were cultured in 37°, 5% CO2. The inhibition on HBV was tested by detg. HBsAg and HBeAg produced by HepG 2.2.15 cells with ELISA technique. The molar ratio between lactose and CMCS was in this covalence conjugate. The best mass ratio of DNA to LacCMCS was 1:10 in DNA/LacCMCS which could deliver gene into cells, and the maximal inhibition rate was 83.6%. In vitro, the lactosaminated carboxymethylchitosan can effectively deliver DNA into cells. .