Reference

Testing the acidic-basic properties of basic food colorants

Testing the acidic-basic properties of basic food colorants. Maslowska, Joanna; Janiak, Jolanta (Zespol Chem. Bionieorg. Anal., Inst. Podstaw Chemii Zywnosci Politech. Lodzkiej, Lodz 90-924, Pol.). Przem. Spozyw., 37(6), 274-8 (Polish) 1983.Some commonly used reagents like 2783-94-0 and 2519-30-4 are used in this experiment. CODEN: PRSPAD. ISSN: 0033-250X. DOCUMENT TYPE: Journal CA Section: 17 (Food and Feed Chemistry) Aq. solns. of the food colorants tartrazine G (C.I.19140) [1934-21-0], Black Blue BN (C.I.28440) [2519-30-4], Yellow Orange S (C.I.15985) [2783-94-0], Amarant acid J (C.I.16185) [915-67-3], and Red cochineal (C.I.16255) [2611-82-7] were analyzed spectrometrically at various wavelengths (200-800 nm), concns., and pHs, and dissocn. and protonation consts. were obtained. The colorants showed weak acidic-basic properties. At pH 6, they behaved as neutral compds. However, strong acid or alk. media increased their dissocn. and protonation. .

Effects of oral administration of azo dyes on RNA synthesis in rat liver nuclei

Effects of oral administration of azo dyes on RNA synthesis in rat liver nuclei. Yoshimoto, Makoto; Hatano, Shoji; Watanabe, Tadao (Fac. Agric., Kyushu Univ., Fukuoka 812, Japan). Shokuhin Eiseigaku Zasshi, 24(4), 408-10 (English) 1983.Some commonly used reagents like 3564-09-8 and 2783-94-0 are used in this experiment. CODEN: SKEZAP. ISSN: 0015-6426. DOCUMENT TYPE: Journal CA Section: 4 (Toxicology) Incorporation of [3H]UTP into RNA, and protein and RNA contents in the nuclei from liver were measured in rats given Ponceau 3R [3564-09-8], Amaranth [915-67-3], or Sunset Yellow FCF [2783-94-0] (300 mg/kg). The RNA incorporation of UTP was greater in nuclei from both Ponceau 3R- and Amaranth-treated rats than in controls. Furthermore, 2 doses of Ponceau 3R increased the RNA contents in liver nuclei. No significant difference was obsd. in the protein content of nuclei isolated from rats treated with these azo dyes or controls. Nuclear prep. from Sunset Yellow FCF-treated rats showed no difference from controls. Thus, Ponceau 3R and Amaranth stimulate in vivo RNA synthesis in rat liver nuclei. .