1126-41-6Relevant articles and documents
Simple H2-free hydrogenation of unsaturated monoterpenoids catalyzed by Raney nickel
Philippov, Alexey A.,Chibiryaev, Andrey M.,Martyanov, Oleg N.
, p. 380 - 381 (2019/08/20)
A series of monoterpenoids (citral, carvone, menthone, camphor) as well as cyclohexanone and hex-5-en-2-one were subjected to transfer hydrogenation with PriOH/Raney nickel system at 82 or 150 °C. Among monoterpenoids, citral and carvone underwent full conversion at 82 °C within 5 h.
Radical chain reduction of alkylboron compounds with catechols
Villa, Giorgio,Povie, Guillaume,Renaud, Philippe
supporting information; experimental part, p. 5913 - 5920 (2011/06/16)
The conversion of alkylboranes to the corresponding alkanes is classically per-formed via protonolysis of alkylboranes. This simple reaction requires the use of severe reaction conditions, that is, treatment with a carboxylic acid at high temperature (>150 °C). We report here a mild radical procedure for the transformation of organoboranes to alkanes. 4-tert-Butylcatechol, a well-established radical inhibitor and antioxidant, is acting as a source of hydrogen atoms. An efficient chain reaction is observed due to the exceptional reactivity of phenoxyl radicals toward alkylboranes. The reaction has been applied to a wide range of organoboron derivatives such as B- alkylcatecholboranes, trialkylboranes, pinacolboronates, and alkylboronic acids. Furthermore, the so far elusive rate constants for the hydrogen transfer between secondary alkyl radical and catechol derivatives have been experimentally determined. Interestingly, they are less than 1 order of magnitude slower than that of tin hydride at 80 °C, making catechols particularly attractive for a wide range of transformations involving C-C bond formation.
Antimicrobial therapeutic compositions for oral and topical use
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Page 7; 18, (2008/06/13)
The invention provides therapeutic antimicrobial compositions comprising natural phenolic compounds and essential oil alcohols and methods of use. The therapeutic antimicrobial compositions are useful to treat internal and external bacterial, fungal, and protozoan infections, as well as antibiotic resistant and secondary opportunistic infections.
