115514-77-7 Usage
Description
3-Chloro-4-methoxybenzenemethanamine is an organic compound that serves as a key intermediate in the synthesis of various pharmaceuticals and chemical compounds. It is characterized by the presence of a chloro group at the 3-position and a methoxy group at the 4-position on a benzene ring, with an amine group attached to the benzene ring through a methylene bridge.
Uses
Used in Pharmaceutical Industry:
3-Chloro-4-methoxybenzenemethanamine is used as a reagent in the synthesis of avanafil (A794670), a medication specifically designed for the treatment of erectile dysfunction. Avanafil works by enhancing the effects of nitric oxide, leading to increased blood flow to the penis and facilitating an erection.
3-Chloro-4-methoxybenzenemethanamine's role in the synthesis of avanafil highlights its importance in the development of therapeutic agents for addressing male sexual health issues. Its unique structural features allow for the creation of molecules with specific biological activities, making it a valuable component in the pharmaceutical industry's pursuit of innovative treatments.
Check Digit Verification of cas no
The CAS Registry Mumber 115514-77-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,5,5,1 and 4 respectively; the second part has 2 digits, 7 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 115514-77:
(8*1)+(7*1)+(6*5)+(5*5)+(4*1)+(3*4)+(2*7)+(1*7)=107
107 % 10 = 7
So 115514-77-7 is a valid CAS Registry Number.
InChI:InChI=1/C8H10ClNO/c1-11-8-3-2-6(5-10)4-7(8)9/h2-4H,5,10H2,1H3
115514-77-7Relevant articles and documents
Preparation method of avanafil important intermediate
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Paragraph 0028; 0029, (2017/04/04)
The invention provides a preparation method of an avanafil important intermediate. The target compound (3-chloro-4-methoxybenzylamine) is prepared according to a route shown as the specification. The preparation method provided by the invention has the advantages of cheap and easily available raw materials, short technical route, mild reaction conditions, low equipment requirement, and small health hazard to operators, and is in line with the idea of green chemistry. The method has high yield, and can obtain product with high purity, thus being suitable for industrial production.
2-(AMINO-SUBSTITUTED)-4-ARYL PYRAMIDINES AND RELATED COMPOUNDS USEFUL FOR TREATING INFLAMMATORY DISEASES
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Page/Page column 129, (2008/06/13)
A heterocyclic inhibitor having the formula (I), with the variables defined herein, which is useful for treating inflammatory and other physiological disorders in which PKC-theta isoform plays a role.