115909-91-6

• 

• Basic information

  1. Product Name: 1-CBZ-4-(2-HYDROXY-ETHYL)-PIPERIDINE
  2. Synonyms: benzyl 4-(2-hydroxyethyl)piperidine-1-carboxylate;1-Piperidinecarboxylic acid, 4-(2-hydroxyethyl)-, phenylMethyl ester;4-(2-HYDROXY-ETHYL)-PIPERIDINE-1-CARBOXYLIC ACID BENZYL ESTER;1-CBZ-4-(2-HYDROXY-ETHYL)-PIPERIDINE;2-(1-BENZYLOXYCARBONYL-4-PIPERIDYL)ETHANOL
  3. CAS NO:115909-91-6
  4. Molecular Formula: C₁₅H₂₁NO₃
  5. Molecular Weight: 263.33
  6. EINECS: N/A
  7. Product Categories: N/A
  8. Mol File: 115909-91-6.mol
  9. Article Data: 16

• Chemical Properties

  1. Melting Point: N/A
  2. Boiling Point: 408.7±28.0 °C(Predicted)
  3. Flash Point: N/A
  4. Appearance: /
  5. Density: 1.140±0.06 g/cm3(Predicted)
  6. Refractive Index: N/A
  7. Storage Temp.: 2-8°C
  8. Solubility: N/A
  9. PKA: 15.10±0.10(Predicted)
  10. CAS DataBase Reference: 1-CBZ-4-(2-HYDROXY-ETHYL)-PIPERIDINE(CAS DataBase Reference)
  11. NIST Chemistry Reference: 1-CBZ-4-(2-HYDROXY-ETHYL)-PIPERIDINE(115909-91-6)
  12. EPA Substance Registry System: 1-CBZ-4-(2-HYDROXY-ETHYL)-PIPERIDINE(115909-91-6)

• Safety Data

  1. Hazard Codes: N/A
  2. Statements: N/A
  3. Safety Statements: N/A
  4. WGK Germany:
  5. RTECS:
  6. HazardClass: N/A
  7. PackingGroup: N/A
  8. Hazardous Substances Data: 115909-91-6(Hazardous Substances Data)

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• 1-Piperidinecarboxylicacid, 4-(2-hydroxyethyl)-, phenylmethyl ester

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115909-91-6 Usage

General Description

1-CBZ-4-(2-HYDROXY-ETHYL)-PIPERIDINE is a chemical compound containing a piperidine ring with a hydroxyethyl group and a carboxybenzyl (CBZ) protecting group. It is a piperidine derivative with potential pharmaceutical applications, particularly in the development of drugs for nervous system disorders. The hydroxyethyl group may contribute to the compound's solubility and potential interactions with biological molecules, while the CBZ protecting group can be selectively removed under mild conditions to reveal the piperidine's primary amine functionality for further chemical modifications. Its structure and functional groups make it a versatile building block for the synthesis of new compounds with potential therapeutic effects.

Check Digit Verification of cas no

The CAS Registry Mumber 115909-91-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,5,9,0 and 9 respectively; the second part has 2 digits, 9 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 115909-91:
(8*1)+(7*1)+(6*5)+(5*9)+(4*0)+(3*9)+(2*9)+(1*1)=136
136 % 10 = 6
So 115909-91-6 is a valid CAS Registry Number.

115909-91-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name	benzyl 4-(2-hydroxyethyl)piperidine-1-carboxylate

1.2 Other means of identification

Product number	-
Other names	2,6-DIBROMOPHENOL ACETATE

1.3 Recommended use of the chemical and restrictions on use

Identified uses	For industry use only.
Uses advised against	no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number	-
Service hours	Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:115909-91-6 SDS

115909-91-6Upstream product

• 501-53-1 benzyl chloroformate 
• 622-26-4 4-(2-Hydroxyethyl)piperidine 
• 19099-93-5 benzyl 4-oxo-1-piperidinecarboxylate 
• 82244-11-9 ethyl-1-carbobenzoxy-Δ^4,α-piperidine-4-acetate 

115909-91-6Downstream Products

• 1242429-10-2 benzyl 4-(2-hydroxypropyl)piperidine-1-carboxylate 
• 1570178-35-6 1-{1-[(benzyloxy)carbonyl]piperidin-4-yl}propan-2-yl 5-(methylsulfonyl)-2,3-dihydro-1H-indole-1-carboxylate 
• 1354925-07-7 (S)-1-(phenylsulfonamido)-2-{4-[2-(piperidin-4-yl)ethoxy]benzamido}ethylthiophosphonic acid 
• 1354925-06-6 (R)-1-(phenylsulfonamido)-2-{4-[2-(piperidin-4-yl)ethoxy]benzamido}ethylthiophosphonic acid 
• 1354925-01-1 (S)-methyl 1-(phenylsulfonamido)-2-{4-[2-(piperidin-4-yl)ethoxy]benzamido}ethylphosphonate 
• 1354925-00-0 (R)-methyl 1-(phenylsulfonamido)-2-{4-[2-(piperidin-4-yl)ethoxy]benzamido}ethylphosphonate 
• 1354924-96-1 (S)-1-(phenylsulfonamido)-2-{4-[2-(piperidin-4-yl)ethoxy]benzamido}ethylphosphonic acid 
• 1354924-94-9 (R)-1-(phenylsulfonamido)-2-{4-[2-(piperidin-4-yl)ethoxy]benzamido}ethylphosphonic acid 
• 1354924-93-8 (S)-1-(phenylsulfonamido)-2-{4-[2-(piperidin-4-yl)ethoxy]benzamido}ethylphosphinic acid 
• 1354924-88-1 (R)-1-(phenylsulfonamido)-2-{4-[2-(piperidin-4-yl)ethoxy]benzamido}ethylphosphinic acid 
• 1354924-66-5 1-(phenylsulfonamido)-2-{4-[2-(piperidin-4-yl)ethoxy]benzamido}ethylthiophosphonic acid 
• 1354924-63-2 methyl 1-(phenylsulfonamido)-2-{4-[2-(piperidin-4-yl)ethoxy]benzamido}ethylphosphonate 
• 1354924-60-9 1-(phenylsulfonamido)-2-{4-[2-(piperidin-4-yl)ethoxy]benzamido}ethylphosphonic acid 
• 1354924-55-2 1-(phenylsulfonamido)-2-{4-[2-(piperidin-4-yl)ethoxy]benzamido}ethylphosphinic acid 

115909-91-6Relevant articles and documents

IRAK DEGRADERS AND USES THEREOF

-

Paragraph 00962; 002759-002761, (2020/06/19)

The present invention provides compounds, compositions thereof, and methods of using the same.

NOVEL COMPOUNDS HAVING ESTROGEN RECEPTOR ALPHA DEGRADATION ACTIVITY AND USES THEREOF

-

Paragraph 0563, (2020/06/08)

The present disclosure relates to novel compounds having estrogen receptor alpha degradation activity, pharmaceutical compositions containing such compounds, and their use in prevention and treatment of cancer and related diseases and conditions.

N-ARYL AND N-HETEROARYL PIPERIDINE DERIVATIVES AS LIVER X RECEPTOR β AGONISTS, COMPOSITIONS, AND THEIR USE

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Page/Page column 105, (2018/04/27)

Provided herein are certain substituted N-aryl and N-heteroaryl piperidine compounds of the formula (I) and pharmaceutically acceptable salts thereof, wherein R1, R2, R3, L, R4, L1, Q, R5 and R 6 are as defined. The said novel compounds, and pharmaceutically acceptable compositions comprising a compound thereof, may be useful as Liver X-β receptor(LXRβ) agonists, and may be useful for treating or preventing pathologies related thereto. Such pathologies include, but are not limited to, inflammatory disease and diseases characterized by defects in cholesterol and lipid metabolism, such as Alzheimer's disease.

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