118348-48-4Relevant articles and documents
Method for preparing cycloheptimidazoles
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, (2008/06/13)
The present invention relates to novel compounds of formula(1). wherein: R1 is hydrogen atom or lower alkyl group, X is bromine atom or chlorine atom; and which are usefull for the preparation of the cycloheptanoides such as cycloheptimidazole derivatives. The compound having formula (1) is obtained in a single pot by the reaction of a trialkylsilylether compound with a dihalocarbene which, in turn, is prepared from the reaction of chloroform or bromoform in the presence of base.