118646-79-0Relevant articles and documents
Erythrocyte-like liposomes prepared by means of amphiphilic cyclodextrin sulfates
Sukegawa, Takeshi,Furuike, Tetsuya,Niikura, Kenichi,Yamagishi, Akihiko,Monde, Kenji,Nishimura, Shin-Ichiro
, p. 430 - 431 (2002)
A novel class of sulfated glycolipids with excellent self-assembling capacity to form stable monolayers at an air-water interface and specific erythrocyte-like liposomes was synthesised from α, β, and γ-cyclodextrins as starting materials.
The 2,3-anhydro-α-cyclomannin-1-propanol hexahydrate: Topography, lipophilicity pattern and solid-state architecture
Immel, Stefan,Lichtenthaler, Frieder W.,Lindner, Hans J.,Fujita, Kahee,Fukudome, Makato,Nogami, Yasuyoshi
, p. 27 - 36 (2000)
As evidenced by its X-ray structural analysis, 2,3-anhydro-α-cyclomannin 6, a cyclooligosaccharide consisting of six α-(1→4)-linked 2,3-anhydro-D-mannopyranose units, readily incorporates 1-propanol into its cavity such that hydrophobic and hydrophilic surface regions of guest and host match at their interfaces. Together with water, the macrocycle and its guest assemble into a unique solid-state architecture, featuring layers of head-to-head dimers of the macrocycle with its guest, separated by equally distinct layers of water molecules, which are engaged in an intense hydrogen bonding network with the 6-CH2OH and the propanol-OH groups. The overall guest-host topography is thus reverse to that of the respective ethanol inclusion complex.1 Copyright (C) 2000 Elsevier Science Ltd.
New cyclodextrin dimers and trimers capable of forming supramolecular adducts with shape-specific ligands
Aime, Silvio,Gianolio, Eliana,Arena, Francesca,Barge, Alessandro,Martina, Katia,Heropoulos, George,Cravotto, Giancarlo
, p. 370 - 379 (2009)
Bridged cyclodextrin dimers and trimers, in which respectively two and three hydrophobic cavities lie in close proximity, display much higher binding affinities and molecular selectivities than do parent cyclodextrins (CDs). By joining βCD units with links inserted at different positions (2-2′, 3-2′, 6-2′ or 6-2′-6″) and interposing spacers of different lengths and shapes, multicavity structures can be synthesized that are precisely tailored to fit specific guest molecules. This enzyme-mimicking strategy can also be used to generate stable supramolecular adducts. A series of CD dimers and trimers was prepared in good yields by carrying out the critical synthetic steps under power ultrasound (US) or microwave (MW) irradiation. Starting from azide and acetylenic CD derivatives, we exploited an efficient MW-promoted Huisgen 1,3-dipolar cycloaddition in the presence of Cu(I) salts. The resulting bridged CD derivatives gave stable adducts with magnetic-resonance-imaging contrast agents (MRI CAs) containing gadolinium(III) chelates. These inclusion complexes were found to be 2 to 3 orders of magnitude more stable than those formed by βCD and to be endowed with high relaxivity values.
Synthesis and monolayer behavior of amphiphilic per(2,3-di-O-alkyl)-α- and β-cyclodextrins and hexakis(6-deoxy-6-thio-2,3-di-O-pentyl)-α-cyclodextrin at an air-water interface
Wazynska, Monika,Temeriusz, Andrzej,Chmurski, Kazimierz,Bilewicz, Renata,Jurczak, Janusz
, p. 9119 - 9123 (2000)
A synthesis of amphiphilic per(2,3-di-O-alkyl)-α- and β-cyclodextrins and hexakis(6-deoxy-6-thio-2,3-di-O-pentyl)-α-cyclodextrin and their monolayer behavior on a water surface is presented. Long alkyl chains were introduced by a treatment of the per(6-O-
Anion binding properties of 2,3-O-dibenzyl-α- and β-cyclodextrin derivatives
Karube, Nobuyuki,Ito, Kazuaki
, p. 719 - 724 (2015/04/14)
Cyclodextrins (CDs) have been investigated as scaffolds for the construction of anion receptors. Modified α- and β-CDs (1a and 1b, respectively), where hydroxyls on C-2 and C-3 are protected by benzyl groups have been synthesized, and their anion binding
