128942-88-1Relevant articles and documents
Synthesis of 1h-indole-2,3-dicarboxylates via rhodium-catalyzed C-H annulation of arylhydrazines with maleates
Bao, Ming,Zhang, Sheng,Li, He,Yamamoto, Yoshinori
, p. 12544 - 12552 (2020)
This work describes a one-step synthesis of 1H-indole-2,3-dicarboxylates through C-H activation. Rhodiumcatalyzed tandem C-H activation and annulation of 2-acetyl-1-phenylhydrazines with maleates proceeded smoothly in the presence of additive NaOAc and oxidant Ag2CO3 and produced the corresponding indole derivatives, 1H-indole-2,3-dicarboxylates, in satisfactory to good yields. A variety of useful functional groups were tolerated on the benzene ring including halogen atoms (F, Cl, Br, and I) and methoxycarbonyl groups.
Synthesis of benzofused 1,4-azaborinols via [4 + 2] annulation strategy and its application in indole synthesis
Chinnapattu, Murugan,Sathiyanarayanan, Kulathu Iyer,Iyer, Pravin S.
, p. 37716 - 37720 (2015/05/13)
We disclose herein, the first general synthesis of benzofused 1,4-azaborinols via [4 + 2] annulation strategy. These compounds have been synthesised from 2-amino phenylboronic acids/boronates and alkynes in excellent yields. Additionally, we demonstrate their synthetic application by reporting the first transformation of benzofused 1,4-azaborinols into functionalized indoles.
Regioselective synthesis of indoles via reductive annulation of nitrosoaromatics with alkynes
Penoni, Andrea,Volkmann, Jerome,Nicholas, Kenneth M.
, p. 699 - 701 (2007/10/03)
(equation presented) Indoles are produced regioselectively and in moderate yields by two new processes: (a) from the [Cp*Ru(CO)2]2-catalyzed reaction of nitrosoaromatics (ArNO) with alkynes under carbon monoxide and (b) in a two-step sequence involving the (uncatalyzed) reaction of ArNO with alkynes, followed by reduction of the intermediate adduct.
