133772-18-6 Usage
Description
2-Iodomethyl benzoic acid methyl ester is a chemical compound belonging to the ester chemical group, characterized by a carbonyl adjacent to an ether linkage. It consists of a methyl benzoic acid molecule substituted with an iodomethyl group, and has a molecular formula of C9H9IO3. 2-Iodomethyl benzoic acid methyl ester is often used in the field of organic synthesis.
Uses
Used in Organic Synthesis:
2-Iodomethyl benzoic acid methyl ester is used as a synthetic intermediate for the preparation of various organic compounds. Its unique structure allows for versatile reactions and transformations, making it a valuable building block in the synthesis of pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Laboratory Research:
In academic and industrial research settings, 2-Iodomethyl benzoic acid methyl ester is utilized as a reagent for studying reaction mechanisms, exploring new synthetic routes, and developing novel chemical methodologies. Its reactivity and functional group compatibility make it a useful tool for advancing the understanding of organic chemistry.
Used in Pharmaceutical Industry:
2-Iodomethyl benzoic acid methyl ester is employed as a key intermediate in the synthesis of certain pharmaceutical compounds. Its unique structural features can be exploited to create new drug candidates with potential therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical sector, 2-Iodomethyl benzoic acid methyl ester is used as a precursor for the development of new pesticides and herbicides. Its chemical properties can be tailored to target specific pests or weeds, contributing to the creation of more effective and environmentally friendly agricultural products.
Safety Considerations:
It is important to handle 2-Iodomethyl benzoic acid methyl ester with care, as it can pose risks if ingested or if it comes into contact with the skin or eyes. Strict adherence to safety guidelines is essential, particularly in laboratory settings, to ensure the well-being of researchers and the integrity of experiments.
Check Digit Verification of cas no
The CAS Registry Mumber 133772-18-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,3,7,7 and 2 respectively; the second part has 2 digits, 1 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 133772-18:
(8*1)+(7*3)+(6*3)+(5*7)+(4*7)+(3*2)+(2*1)+(1*8)=126
126 % 10 = 6
So 133772-18-6 is a valid CAS Registry Number.
InChI:InChI=1/C9H9IO2/c1-12-9(11)8-5-3-2-4-7(8)6-10/h2-5H,6H2,1H3
133772-18-6Relevant articles and documents
Catalytic Halogen Bond Activation in the Benzylic C-H Bond Iodination with Iodohydantoins
Combe, Sascha H.,Hosseini, Abolfazl,Song, Lijuan,Hausmann, Heike,Schreiner, Peter R.
, p. 6156 - 6159 (2017)
This letter presents the side-chain iodination of electron-deficient benzylic hydrocarbons at rt using N-hydroxyphthalimide (NHPI) as radical initiator and 1,3-diiodo-5,5-dimethylhydantoin and 3-iodo-1,5,5-trimethylhydantoin (3-ITMH) as iodine source. Addition of a carboxylic acid increased the reactivity due to complex formation with and activation of 3-ITMH by proton transfer and halogen bond formation. No SEAr reactions were observed under the employed reaction conditions. Our method enables convenient product isolation and gives 50-72% yields of isolated products.
