151449-78-4 Usage
General Description
4-Hydroxy-1-methyl-2-oxo-1,2-dihydro-quinoline-3-carboxylic acid (2-amino-phenyl)-amide is a chemical compound with potential pharmaceutical applications. It is a synthetic derivative of quinoline, a heterocyclic compound commonly found in pharmacologically active molecules. This particular compound contains a hydroxy group, a methyl group, and an oxo group in its structure, as well as an amino-phenyl amide side chain. These features make it a potentially interesting compound for further study as a potential drug candidate for the treatment of various conditions. Its precise pharmacological properties and potential therapeutic applications would require further research and testing.
Check Digit Verification of cas no
The CAS Registry Mumber 151449-78-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,1,4,4 and 9 respectively; the second part has 2 digits, 7 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 151449-78:
(8*1)+(7*5)+(6*1)+(5*4)+(4*4)+(3*9)+(2*7)+(1*8)=134
134 % 10 = 4
So 151449-78-4 is a valid CAS Registry Number.
InChI:InChI=1/C17H15N3O3/c1-20-13-9-5-2-6-10(13)15(21)14(17(20)23)16(22)19-12-8-4-3-7-11(12)18/h2-9,23H,18H2,1H3,(H,19,22)
151449-78-4Relevant articles and documents
Synthesis, X-ray crystallographic study, and biological evaluation of coumarin and quinolinone carboxamides as anticancer agents
Matiadis, Dimitris,Stefanou, Valentina,Athanasellis, Giorgos,Hamilakis, Stylianos,McKee, Vickie,Igglessi-Markopoulou, Olga,Markopoulos, John
, p. 1063 - 1069 (2013/07/26)
A series of coumarin and quinolinone-3-aminoamide derivatives was synthesized and evaluated for its potency in inhibition of cancer cell growth. The structure of N-[2-(dimethylamino) ethyl]-4-hydroxy-2-oxo-1-phenyl-1,2- dihydroquinoline-3-carboxamide was
4-HYDROXY-2-QUINOLONES 7. SYNTHESIS AND BIOLOGICAL PROPERTIES OF 1-R-3-(2-BENZIMIDAZOLYL)-4-HYDROXY-2-QUINOLONES
Ukrainets, I.V.,Bezuglyi, P.A.,Gorokhova, O.V.,Treskach, V.I.,Turov, A.V.
, p. 92 - 94 (2007/10/02)
Condensation of 1-R-3-carbethoxy-4-hydroxy-2-quinolones with o-phenylene diamine gives the corresponding 1-R-3-(2-benzimidazolyl)-4-hydroxy-2-quinolones.Data on a study of the antihyroid activity of the synthesized compounds is presented.
