161609-84-3 Usage
General Description
1-N-Cbz-4-cyanopiperidine is a chemical compound that contains a Cbz (carboxybenzyl) protective group on the nitrogen atom and a cyanide group attached to the piperidine ring. It is commonly used as an intermediate in the synthesis of pharmaceuticals and other organic compounds. The Cbz group serves to protect the nitrogen atom from unwanted reactions, while the cyanide group provides a reactive site for further functionalization. 1-N-Cbz-4-cyanopiperidine has applications in the development of new drugs and can be utilized in the production of various organic molecules with diverse biological activities. Overall, 1-N-Cbz-4-cyanopiperidine is an important building block in organic synthesis.
Check Digit Verification of cas no
The CAS Registry Mumber 161609-84-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,1,6,0 and 9 respectively; the second part has 2 digits, 8 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 161609-84:
(8*1)+(7*6)+(6*1)+(5*6)+(4*0)+(3*9)+(2*8)+(1*4)=133
133 % 10 = 3
So 161609-84-3 is a valid CAS Registry Number.
InChI:InChI=1/C14H16N2O2/c15-10-12-6-8-16(9-7-12)14(17)18-11-13-4-2-1-3-5-13/h1-5,12H,6-9,11H2
161609-84-3Relevant articles and documents
SUBSTITUTED HETEROCYCLIC COMPOUNDS AS TROPOMYOSIN RECEPTOR KINASE A (TRKA) INHIBITORS
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Paragraph 0597 - 0599; 1156 - 1158, (2015/02/05)
The present application relates to a series of substituted pyrazolo[1,5-a]pyridine compounds, their use as tropomyosin receptor kinase (Trk) family protein kinase inhibitors, method of making and pharmaceutical compositions comprising such compounds.
Nitrilase-catalyzed enantioselective synthesis of pyrrolidine- And piperidinecarboxylic acids
Winkler, Margit,Meischler, Dorith,Klempier, Norbert
, p. 1475 - 1480 (2008/09/16)
The enantioselective synthesis of the nonproteinogenic amino acids β-proline and nipecotic acids from their readily available nitriles is achieved in high enantiomeric excess by commercially available nitrilases. The presented procedure comprises not more than 4 steps, thus considerably reducing the multiple steps generally required. Amide formation is also observed for specific heterocyclic nitriles.