16511-38-9Relevant articles and documents
Fast and calibration free determination of first order reaction kinetics in API synthesis using in-situ ATR-FTIR
Rehbein, Moritz C.,Husmann, Sascha,Lechner, Christian,Kunick, Conrad,Scholl, Stephan
, p. 95 - 100 (2017/10/23)
In early stages of drug development only sparse amounts of the key substances are available, which is problematic for the determination of important process data like reaction kinetics. Therefore, it is important to perform experiments as economically as
Discovery of the imidazo[1,5-a][1,2,4]-triazolo[1,5-d][1,4]benzodiazepine scaffold as a novel, potent and selective GABAA α5 inverse agonist series
Achermann, Guido,Ballard, Theresa M.,Blasco, Francesca,Broutin, Pierre-Emmanuel,Buettelmann, Bernd,Fischer, Holger,Graf, Martin,Hernandez, Maria-Clemencia,Hilty, Peter,Knoflach, Frederic,Koblet, Andreas,Knust, Henner,Kurt, Anke,Martin, James R.,Masciadri, Raffaello,Porter, Richard H.P.,Stadler, Heinz,Thomas, Andrew W.,Trube, Gerhard,Wichmann, Juergen
scheme or table, p. 5746 - 5752 (2010/04/30)
Through iterative design cycles we have discovered a number of novel new classes where the imidazo[1,5-a][1,2,4]-triazolo[1,5-d][1,4]benzodiazepine was deemed the most promising GABAA α5 inverse agonist class with potential for cognitive enhanc
LACTAM COMPOUNDS USEFUL AS PROTEIN KINASE INHIBITORS
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Page/Page column 310, (2008/06/13)
The present invention provides novel compounds useful as inhibitors of protein kinases. The invention also provides pharmaceutical compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various diseases.