1672-88-4 Usage
Chemical Properties
Yellow Solid
Uses
Furagin (a nitrofurantoin analog) has the same efficacy in treating acute cystitis as Ciprofloxacin, however the duration of therapy is longer. Antibacterial.
Definition
ChEBI: An imidazolidine-2,4-dione that is hydantoin substituted at position 1 by a [3-(5-nitro-2-furyl)prop-2-en-1-ylidene]amino group (the configuration of the C2C and C2
bonds in the grouping that links the two heterocycles is not specified). A nitrofuran antibiotic with properties similar to nitrofurantoin, furagin is used in the treatment of urinary tract infections.
Check Digit Verification of cas no
The CAS Registry Mumber 1672-88-4 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,6,7 and 2 respectively; the second part has 2 digits, 8 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1672-88:
(6*1)+(5*6)+(4*7)+(3*2)+(2*8)+(1*8)=94
94 % 10 = 4
So 1672-88-4 is a valid CAS Registry Number.
InChI:InChI=1/C10H8N4O5/c15-8-6-13(10(16)12-8)11-5-1-2-7-3-4-9(19-7)14(17)18/h1-5H,6H2,(H,12,15,16)/b2-1+,11-5+
1672-88-4Relevant articles and documents
Synthesis method of 1-((3-(5-nitro-2-furyl)allylidene)amino) hydantoin
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Paragraph 0043; 0045; 0046; 0047; 0050; 0052; 0054, (2018/11/22)
The invention discloses a synthesis method of 1-((3-(5-nitro-2-furyl)allylidene)amino) hydantoin. The synthesis method is characterized by including: taking 5-nitrofuranacrolein and propyl aminohydantoin as main raw materials, allowing one-step condensation reaction to prepare a target compound crude product, and refining and purifying N, N-dimethylformamide to obtain 1-((3-(5-nitro-2-furyl)allylidene)amino) hydantoin, wherein a chemical reaction formula is shown as follows. Compared with reported methods, the synthesis method has the advantages that reaction path is short, process is simple and convenient, the raw materials are easy to get, generation of a pollution byproduct-aldehyde during synthesis is avoided, and the method is high in yield, low in cost, few in three wastes and environment-friendly, and reaction conversion rate reaches 98%.
