17180-94-8 Usage
Description
5-Chloropyrimidine, a chlorinated derivative of the heterocyclic compound pyrimidine, is a chemical compound with the molecular formula C4H3ClN2. It is commonly found in DNA and RNA and is primarily used in the synthesis of pharmaceuticals, agrochemicals, dyes, pigments, and other organic compounds. As a colorless to pale yellow liquid with a strong, pungent odor, 5-Chloropyrimidine is classified as a hazardous substance due to its irritating and corrosive properties. Its toxicity to aquatic organisms necessitates careful handling and disposal. Overall, 5-Chloropyrimidine plays a crucial role in the chemical and pharmaceutical industries, but its use requires careful consideration of its potential risks and hazards.
Uses
Used in Pharmaceutical Industry:
5-Chloropyrimidine is used as an intermediate in the synthesis of various pharmaceuticals for its ability to contribute to the development of new drugs and therapeutic agents.
Used in Agrochemical Industry:
5-Chloropyrimidine is used as a building block in the production of agrochemicals, such as pesticides and herbicides, due to its potential to enhance the effectiveness of these products.
Used in Dye and Pigment Industry:
5-Chloropyrimidine is used as a key component in the creation of dyes and pigments, contributing to the color and stability of these compounds in various applications.
Used in Organic Compounds Production:
5-Chloropyrimidine is used as a precursor in the synthesis of other organic compounds, enabling the development of a wide range of chemical products with diverse applications.
Check Digit Verification of cas no
The CAS Registry Mumber 17180-94-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,7,1,8 and 0 respectively; the second part has 2 digits, 9 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 17180-94:
(7*1)+(6*7)+(5*1)+(4*8)+(3*0)+(2*9)+(1*4)=108
108 % 10 = 8
So 17180-94-8 is a valid CAS Registry Number.
InChI:InChI=1/C4H3ClN2/c5-4-1-6-3-7-2-4/h1-3H
17180-94-8Relevant articles and documents
Bridged Hydroquinolines
Balasubrahmanyam, S. N.,Jeyashri, B.
, p. 559 - 562 (2007/10/02)
The pyridannulation procedure of condensing vinamidinium salts with ketones having a free α-methylene has been adapted to prepare 3-substituted 5,6,7,8-tetrahydroquinolines; characterization data for the seven systems synthesized are reported.Conditions required are less drastic than those for recently reported alternative approaches to analogous systems.The adaption has considerable generality even though 5,8-methano-bridged 5,6,7,8-tetrahydroquinolines are not accessible through it.Chirality in the starting ketone, not affected by exposure to enolizing conditions, is preserved in the pyridannulated products.
Process for preparing 5-halopyrimidines
-
, (2008/06/13)
The reaction of formamide at high temperature with a 4-halo-5-hydroxy-2(5H)-furanone provides high yields of 5-chloro or 5-bromopyrimidines.
Reactions of Halogenomethanes in the Vapour Phase. Part 5. The Reactions of Imidazolines, Anils, and 1-Methylimidazole with Chloroform at 550 deg C, and a Comparison with their Liquid-Phase Reactions with Trichloroacetate Ion or Hexachloroacetone and Base
Busby, Reginald E.,Khan, Mohammad A.,Khan, Mohammad R.,Parrick, John,Shaw, C. J. Granville
, p. 1431 - 1435 (2007/10/02)
The vapor-phase reactions of imidazolines and anils with chloroform at 550 deg C are compared with their liquid-phase reactions in the presence of hexachloroacetone and base or upon thermolysis with trichloroacetate ion.In the vapour-phase reactions imidazolines, unlike imidazoles, gave non-chlorinated pyrimidines, and 1-methyl-imidazole gave 2-cyanopyrrole and the four 3-chlorocyanopyridines.