34771-45-4

Basic information

• Product Name: 5-PHENYL-PYRIMIDINE
• Synonyms: 5-PHENYL-PYRIMIDINE;5-Phenylpryimidine
• CAS NO: 34771-45-4
• Molecular Formula: C₁₀H₈N₂
• Molecular Weight: 156.18
• Mol File: 34771-45-4.mol
• Article Data: 128

Chemical Properties

• Boiling Point: 297.8 °C at 760 mmHg
• Flash Point: 141.3 °C
• Appearance: /
• Density: 1.106 g/cm³
• Vapor Pressure: 0.00234mmHg at 25°C
• Refractive Index: 1.58
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 5-PHENYL-PYRIMIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-PHENYL-PYRIMIDINE(34771-45-4)
• EPA Substance Registry System: 5-PHENYL-PYRIMIDINE(34771-45-4)

Safety Data

• Hazardous Substances Data: 34771-45-4(Hazardous Substances Data)

Usage

General Description

5-Phenyl-Pyrimidine is a chemical compound classified under the family of pyrimidines. It is an aromatic organic compound that consists of a pyrimidine ring fused to a phenyl group. Although relatively lesser-known, 5-Phenyl-pyrimidine forms the basis for the construction of more complex molecules which can have medicinal or practical uses. It is often used as a precursor to synthesize various organic substances and as a component in certain pharmaceutical drugs. Its properties and behavior can vary depending on how it is manipulated chemically.

InChI:InChI=1/C10H8N2/c1-2-4-9(5-3-1)10-6-11-8-12-7-10/h1-8H

Upstream product

• 60122-80-7 4-chloro-5-phenylpyrimidine 
• 24903-95-5 nopinone 
• 7089-34-1 ((E)-3-Dimethylamino-2-phenyl-allylidene)-dimethyl-ammonium; perchlorate 
• 4595-59-9 5-bromopyrimidine 
• 100-59-4 phenylmagnesium chloride 
• 98-80-6 phenylboronic acid 
• 17180-94-8 5-chloropyrimidine 
• 289-95-2 PYRIMIDINE 
• 591-50-4 iodobenzene 
• 109299-78-7 pyrimidine 5-boronic acid 
• 71-43-2 benzene 
• 119072-55-8 tert-butylisonitrile 
• 3473-63-0 formamidine acetic acid 
• 536-74-3 phenylacetylene 

Downstream Products

• 1261868-54-5 2-iodo-5-phenylpyrimidine 
• 68049-21-8 5-(4-fluorophenyl)pyrimidine 
• 114969-62-9 5-phenylpyrimidine-4-carbonitrile 
• 114969-91-4 5-Phenyl-pyrimidine-4,6-dicarbonitrile 
• 85386-18-1 2-Cyano-5-phenylpyrimidine 
• 114969-47-0 5-Phenyl-pyrimidine 1-oxide 
• 21419-05-6 4-amino-5-phenylpyrimidine 

Relevant articles and documents

Selective Synthesis of Substituted Pyridines and Pyrimidines through Cascade Annulation of Isopropene Derivatives

Diverse substituted pyridines and pyrimidines with high selectivity were obtained using a concise and efficient protocol developed herein. The reaction proceeds via metal-free cascade annulation of isopropene derivatives. Using isopropene derivatives as C3 synthons, NH4I as the “N” source, and formaldehyde or dimethyl sulfoxide as the carbon source, this reaction realizes the efficient formation of intermolecular C-N and C-C bonds.

An unsymmetrical Schiff-base derived recyclable Pd-catalyst for Suzuki–Miyaura and Sonogashira reactions in aqueous media

Abstract: A water-soluble palladium (II) complex containing an unsymmetrical Schiff-base ligand was synthesized and applied as catalyst Suzuki–Miyaura and Sonogashira cross-coupling reactions in aqueous media. Notably, moderate to excellent yields of biaryls were obtained in Suzuki reaction with usually less reactive aryl and heteroaryl chlorides under relatively mild condition. Moderate-to-high yields of aryl-alkynes were also obtained in Sonogashira reactions using aryl bromides. Apart from hydrophilic nature, the accomplishment of reactions in water, high recyclability, broad functional group tolerance, etc., are other advantages of the system. Graphic abstract: [Figure not available: see fulltext.]

Fe3O4-SAHPG-Pd0 nanoparticles: A ligand-free and low Pd loading quasiheterogeneous catalyst active for mild Suzuki–Miyaura coupling and C-H activation of pyrimidine cores

This paper reports a green magnetic quasiheterogeneous efficient palladium catalyst in which Pd0 nanoparticles have been immobilized in self-assembled hyperbranched polyglycidole (SAHPG)-coated magnetic Fe3O4 nanoparticles (Fe3O4-SAHPG-Pd0). This catalyst has been used for effective ligandless Pd catalyzed Suzuki–Miyaura coupling reactions of different aryl halides with substituted boronic acids at room temperature and in aqueous media. Herein, SAHPG is used as support; it also acts as a reducing agent and stabilizer to promote the transformation of PdII to Pd0 nanoparticles. Also, this environmental friendly quasiheterogeneous catalyst is employed for the first time in the synthesis of new pyrimido[4,5-b]indoles via oxidative addition/C-H activation reactions on the pyrimidine rings, which were obtained with higher yield and faster than when Pd(OAc)2 was used as the catalyst. Interestingly, the above-mentioned catalyst could be recovered in a facile manner from the reaction mixture by applying an external magnet device and recycled several times with no significant decrease in the catalytic activity.