178376-63-1Relevant articles and documents
Investigation of trypanothione reductase inhibitory activity by 1,3,4-thiadiazolium-2-aminide derivatives and molecular docking studies
Rodrigues, Raquel F.,Castro-Pinto, Denise,Echevarria, Aurea,Dos Reis, Camilla M.,Del Cistia, Catarina N.,Sant'Anna, Carlos Mauricio R.,Teixeira, Filipa,Castro, Helena,Canto-Cavalheiro, Marilene,Leon, Leonor L.,Tomas, Ana
experimental part, p. 1760 - 1766 (2012/04/10)
The biological activities of a series of mesoionic 1,3,4-thiadiazolium-2- aminide derivatives have been studied. The most active compounds (MI-HH; MI-3-OCH3; MI-4-OCH3 and MI-4-NO2) were evaluated to determine their effect