18717-73-2 Usage
Description
8-Benzyl-8-azabicyclo[3.2.1]octan-3-endo-ol, also known as BNJ-716-12, is a complex organic chemical compound with a bicyclic structure. It features an eight-membered ring with an amine group and a three-membered ring with a hydroxy group. The presence of a benzyl group, which is a phenyl group bonded to a CH2 group, adds to its versatility for chemical synthesis and reactions.
Uses
Used in Chemical Synthesis:
8-Benzyl-8-azabicyclo[3.2.1]octan-3-endo-ol is used as a key intermediate in the synthesis of various complex organic compounds. Its unique structure allows for a wide range of chemical reactions, making it a valuable building block in the development of new molecules.
Used in Pharmaceutical Industry:
8-Benzyl-8-azabicyclo[3.2.1]octan-3-endo-ol is used as a potential drug candidate for the development of new therapeutic agents. Its versatile structure enables it to interact with various biological targets, offering potential applications in the treatment of different diseases.
Used in Material Science:
8-Benzyl-8-azabicyclo[3.2.1]octan-3-endo-ol is used as a component in the development of advanced materials, such as polymers and composites. Its unique chemical properties can contribute to the creation of materials with improved properties, such as enhanced strength, flexibility, or thermal stability.
Used in Research and Development:
8-Benzyl-8-azabicyclo[3.2.1]octan-3-endo-ol is used as a research tool in academic and industrial laboratories. Its complex structure and reactivity make it an interesting subject for studying various chemical reactions and processes, contributing to the advancement of scientific knowledge.
Check Digit Verification of cas no
The CAS Registry Mumber 18717-73-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,8,7,1 and 7 respectively; the second part has 2 digits, 7 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 18717-73:
(7*1)+(6*8)+(5*7)+(4*1)+(3*7)+(2*7)+(1*3)=132
132 % 10 = 2
So 18717-73-2 is a valid CAS Registry Number.
InChI:InChI=1/C14H19NO/c16-14-8-12-6-7-13(9-14)15(12)10-11-4-2-1-3-5-11/h1-5,12-14,16H,6-10H2/t12-,13+,14+
18717-73-2Relevant articles and documents
Contra-thermodynamic Hydrogen Atom Abstraction in the Selective C-H Functionalization of Trialkylamine N-CH3 Groups
Barham, Joshua P.,John, Matthew P.,Murphy, John A.
supporting information, p. 15482 - 15487 (2016/12/09)
We report a simple one-pot protocol that affords functionalization of N-CH3 groups in N-methyl-N,N-dialkylamines with high selectivity over N-CH2R or N-CHR2 groups. The radical cation DABCO+?, prepared in situ by oxidation of DABCO with a triarylaminium salt, effects highly selective and contra-thermodynamic C-H abstraction from N-CH3 groups. The intermediates that result react in situ with organometallic nucleophiles in a single pot, affording novel and highly selective homologation of N-CH3 groups. Chemoselectivity, scalability, and recyclability of reagents are demonstrated, and a mechanistic proposal is corroborated by computational and experimental results. The utility of the transformation is demonstrated in the late-stage site-selective functionalization of natural products and pharmaceuticals, allowing rapid derivatization for investigation of structure-activity relationships.
HETEROARYL DERIVATIVES FOR THE TREATMENT OF RESPIRATORY DISEASES
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Page/Page column 118; 119, (2015/06/18)
The invention relates to novel compounds of formula (I) which are both phosphodiesterase 4 (PDE4) enzyme inhibitors and muscarinic M3 receptor antagonists, methods of preparing such compounds, compositions containing them and therapeutic use thereof.
Azabicyclo[3.2.1]octan-3α-yl and azabicyclo[3.3.1]nonan-3α-yl carbamates as σ2-selective radiotracers
Yang,Whirrett,Wu,Wheeler,Childers,Mach
, p. S684-S686 (2007/10/03)
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