19481-82-4Relevant articles and documents
2,4,4,6-Tetrabromocyclohexa-2,5-dienone in the presence of triphenylphosphine as a specific reagent for nucleophilic substitution in cyanohydrins
Matveeva, Elena D.,Podrugina, Tatyana A.,Tishkovskaya, Elena V.,Zefirov, Nikolai S.
, p. 260 - 261 (2003)
A convenient method for the synthesis of α-bromonitriles from aliphatic cyanohydrins using the 2,4,4,6-tetrabromocyclohexa-2,5-dienone complex with triphenylphosphine was developed.
(2-Cyanoallyl)trimethylsilane and (2-Cyanoethyl)trimethylsilane. Unique ?? Captodative Systems
Sakurai, Hideki,Kyushin, Soichiro,Nakadaira, Yasuhiro
, p. 297 - 300 (1987)
Addition reactions of (2-cyanoallyl)trimethylsilane as well as hydrogen abstraction reactions of (2-cyanoethyl)trimethylsilane were examined.These compounds exhibit high reactivities in free-radical reactions, demonstrating existence of the ?? captodative effect.
Nickel-catalyzed direct alkylation of heterocycles with α-bromo carbonyl compounds: C3-selective functionalization of 2-pyridones
Nakatani, Akihiro,Hirano, Koji,Satoh, Tetsuya,Miura, Masahiro
supporting information, p. 7691 - 7695 (2013/07/05)
Nickel HAS it: A Ni(cod)2/dppp catalyst system promotes the direct alkylation of electron-rich heterocycles with α-bromo carbonyl compounds and involves an alkyl radical intermediate (see scheme; cod=1,5-cyclooctadiene, dppp=1,3-bis(diphenylphosphino)propane). This homolytic radical aromatic substitution (HAS)-type reaction enables the C3-selective direct functionalization of 2-pyridones. Copyright