19522-39-5Relevant articles and documents
A novel immunostimulator, N2-[α-O-Benzyl-N-(acetylmuramyl) -L-alanyl-D-isoglutaminyl]-N6-trans-(m-nitrocinnamoyl)-L-lysine, and its adjuvancy on the hepatitis B surface antigen
Yang, Hong-Zhen,Xu, Song,Liao, Xue-Yan,Zhang, Suo-De,Liang, Zheng-Lun,Liu, Bai-He,Bai, Jin-Ye,Jiang, Chao,Ding, Jian,Cheng, Gui-Fang,Liu, Gang
, p. 5112 - 5122 (2005)
N2-[α-O-Benzyl-N-(acetylmuramyl)-L-alanyl-D-isoglutaminyl] -N6-trans-(m-nitrocinnamoyl)-L-lysine (muramyl dipeptide C, or MDP-C) has been synthesized as a novel, nonspecific immunomodulator. The present study shows that MDP-C induces
Convergent synthesis of novel muramyl dipeptide analogues: Inhibition of porphyromonas gingivalis-induced pro-inflammatory effects by high doses of muramyl dipeptide
Cai, Bin,Panek, James S.,Amar, Salomon
, p. 6878 - 6890 (2016/08/05)
Porphyromonas gingivalis (P.g.)-induced TNF-α can be affected by muramyl dipeptide (MDP) in a biphasic concentration-dependent manner. We found that in P.g.-exposed macrophages, treatment with 10 μg/mL of MDP (MDP-low) up-regulated TNF-α by 29%, while 100