1971-59-1

• 

• Basic information

  1. Product Name: 17,17-dimethyl-18-norandrosta-4,13-dien-3-one
  2. Synonyms: 17,17-dimethyl-18-norandrosta-4,13-dien-3-one
  3. CAS NO:1971-59-1
  4. Molecular Formula: C₂₀H₂₈O
  5. Molecular Weight: 284.44
  6. EINECS: N/A
  7. Product Categories: N/A
  8. Mol File: 1971-59-1.mol
  9. Article Data: 5

• Chemical Properties

  1. Melting Point: N/A
  2. Boiling Point: 411.9°C at 760 mmHg
  3. Flash Point: 191.5°C
  4. Appearance: /
  5. Density: 1.06g/cm³
  6. Vapor Pressure: 5.38E-07mmHg at 25°C
  7. Refractive Index: 1.553
  8. Storage Temp.: N/A
  9. Solubility: N/A
  10. CAS DataBase Reference: 17,17-dimethyl-18-norandrosta-4,13-dien-3-one(CAS DataBase Reference)
  11. NIST Chemistry Reference: 17,17-dimethyl-18-norandrosta-4,13-dien-3-one(1971-59-1)
  12. EPA Substance Registry System: 17,17-dimethyl-18-norandrosta-4,13-dien-3-one(1971-59-1)

• Safety Data

  1. Hazard Codes: N/A
  2. Statements: N/A
  3. Safety Statements: N/A
  4. WGK Germany:
  5. RTECS:
  6. HazardClass: N/A
  7. PackingGroup: N/A
  8. Hazardous Substances Data: 1971-59-1(Hazardous Substances Data)

• Suppliers
• Usage
• SDS
• Upstream product
• Downstream Products
• Article

1971-59-1 Suppliers

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• 18-Norandrosta-4,13-dien-3-one,17,17-dimethyl- (8CI,9CI)

  Cas No: 1971-59-1

• USD $ 3.0-3.0 / Kilogram

• 1 Kilogram

• 1-100 Metric Ton/Month

• Dayang Chem (Hangzhou) Co.,Ltd.
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• Pharmaceutical Grade CAS 1971-59-1 with competitive price

  Cas No: 1971-59-1

• USD $ 139.0-210.0 / Kilogram

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• Zhuozhou Wenxi import and Export Co., Ltd
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• 1971-59-1

  Cas No: 1971-59-1

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• Henan Tianfu Chemical Co., Ltd.
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• 18-Norandrosta-4,13-dien-3-one,17,17-dimethyl- (8CI,9CI) cas 1971-59-1

  Cas No: 1971-59-1

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• Hangzhou Fandachem Co.,Ltd
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• 17,17-dimethyl-18-norandrosta-4,13-dien-3-one

  Cas No: 1971-59-1

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• Shanghai Run-Biotech Co., Ltd.
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1971-59-1 Usage

General Description

17,17-dimethyl-18-norandrosta-4,13-dien-3-one, also known as Mibolerone, is a synthetic anabolic steroid with potent androgenic properties. It is a derivative of nandrolone and has been used in veterinary medicine to promote muscle growth and stimulate appetite in animals. In humans, Mibolerone has been studied for its potential use in hormone replacement therapy, but its use is limited due to its high potency and potential for adverse side effects. It is classified as a controlled substance and is illegal to use without a prescription. Mibolerone is known to have a high risk of liver toxicity and suppression of natural testosterone production, making it a controversial and dangerous choice for athletic performance enhancement.

Check Digit Verification of cas no

The CAS Registry Mumber 1971-59-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,9,7 and 1 respectively; the second part has 2 digits, 5 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1971-59:
(6*1)+(5*9)+(4*7)+(3*1)+(2*5)+(1*9)=101
101 % 10 = 1
So 1971-59-1 is a valid CAS Registry Number.

InChI:InChI=1/C20H28O/c1-19(2)10-9-16-15-5-4-13-12-14(21)8-11-20(13,3)18(15)7-6-17(16)19/h12,15,18H,4-11H2,1-3H3/t15-,18-,20-/m0/s1

1971-59-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name	(8R,9S,10R)-10,17,17-trimethyl-1,2,6,7,8,9,11,12,15,16-decahydrocyclopenta[a]phenanthren-3-one

1.2 Other means of identification

Product number	-
Other names	17,17-Dimethyl-18-norandrostan-4,13-dien-3-on

1.3 Recommended use of the chemical and restrictions on use

Identified uses	For industry use only.
Uses advised against	no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number	-
Service hours	Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1971-59-1 SDS

1971-59-1Upstream product

• 846-44-6 3β-hydroxy-10.13-dimethyl-17-methylene-gonene-(5) 
• 53-43-0 dehydroepiandrosterone 
• 846-45-7 17-Methylene-4-androstene-3-one 
• 434-03-7 levonorgestrel 
• 21509-30-8 13ξ-Hydroxy-17,17-dimethyl-12(13-14)abeo-18-nor-androsten-(4)-on-(3) 
• 143579-42-4 methyltestosterone 17β-sulfate pyridinium salt 
• 58-18-4 17-methyltestosterone 

1971-59-1Downstream Products

1971-59-1Relevant articles and documents

Structure-activity relationship and mechanistic study on guggulsterone derivatives; Discovery of new anti-pancreatic cancer candidate

Kohyama, Aki,Kim, Min Jo,Yokoyama, Rei,Sun, Sijia,Omar, Ashraf M.,Phan, Nguyen Duy,Meselhy, Meselhy R.,Tsuge, Kiyoshi,Awale, Suresh,Matsuya, Yuji

, (2021/12/24)

Pancreatic cancer is one of the deadliest types of malignancies. A new intervention aiming to combat pancreatic cancer is targeting its extra-ordinary ability to tolerate nutrition starvation, a phenomenon known as “Austerity”. As a part of a research program aiming to develop a new-generation of anticancer agents, known as “anti-austerity agents”, guggulsterone derivatives (GSDs) were identified as unique anti-austerity agents in terms of potency and selectivity. These agents are able to exert preferential cytotoxic activity only under nutrient-deprived conditions with little or no toxicity under normal conditions. In the present study, a library of 14 GSDs was synthesized and screened against PANC-1 human pancreatic cells. Among tested compounds, GSD-11 showed the most potent activity with PC50 a value of 0.72 μM. It also inhibited pancreatic cancer cell migration and colony formation in a concentration-dependent manner. A mechanistic study revealed that this compound can inhibit the activation of the Akt/mTOR signaling pathway. Therefore, GSD-11 could be a promising lead compound for the anticancer drug discovery against pancreatic cancer.

Studies on anabolic steroids. 9. Tertiary sulfates of anabolic 17α-methyl steroids: synthesis and rearrangement

Bi, Honggang,Masse, Robert,Just, George

, p. 306 - 312 (2007/10/02)

A simple and convenient method has been developed to prepare sulfates of anabolic 17β-hydroxy-17α-methyl steroids.The sulfates of methandienone, 17α-methyltestosterone, mestanolone, oxandrolone, and stanozolol were prepared.Different A-ring functions were not affected under the sulfation condition.The buffered hydrolyses of these sulfates provided the 17-epimers of the original steroids and 17,17-dimethyl-18-nor-13(14)-ene steroids, presumably via the 17-carbocations. Keywords: steroids, tertiary sulfates; 17α-methyl steroids; 17β-methyl steroids; 17,17-dimethyl-18-norandrost-13(14)-enes; NMR

Influence of the steroid A ring on the reactivity at the level of carbons 13 and 14. II. The BF3-catalyzed oxirane ring opening of the 13,14-epoxy steroids in the estrone and testosterone series

Torreilles,Crastes de Paulet

, p. 4886 - 4892 (2007/10/06)

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