1001353-87-2

Basic information

• Product Name: (S)-1-(tert-Butoxycarbonyl)-4,4-diMethylpyrrolidine-2-carboxylic acid
• CAS NO: 1001353-87-2
• Molecular Formula: C₁₂H₂₁NO₄
• Molecular Weight: 243.29944
• Mol File: 1001353-87-2.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (S)-1-(tert-Butoxycarbonyl)-4,4-diMethylpyrrolidine-2-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-1-(tert-Butoxycarbonyl)-4,4-diMethylpyrrolidine-2-carboxylic acid(1001353-87-2)
• EPA Substance Registry System: (S)-1-(tert-Butoxycarbonyl)-4,4-diMethylpyrrolidine-2-carboxylic acid(1001353-87-2)

Safety Data

• Hazardous Substances Data: 1001353-87-2(Hazardous Substances Data)

Usage

General Description

(S)-1-(tert-Butoxycarbonyl)-4,4-dimethylpyrrolidine-2-carboxylic acid is a chemical compound with a molecular formula of C15H25NO4. It is a derivative of pyrrolidine and is commonly used as a building block in organic synthesis and medicinal chemistry. (S)-1-(tert-Butoxycarbonyl)-4,4-dimethylpyrrolidine-2-carboxylic acid is often utilized as a protecting group for the acid-sensitive amines and it can also act as a chiral auxiliary in asymmetric synthesis. Its tert-butoxycarbonyl (Boc) protecting group helps to prevent unwanted reactions at specific positions on a molecule while the pyrrolidine core provides stability and flexibility. (S)-1-(tert-Butoxycarbonyl)-4,4-dimethylpyrrolidine-2-carboxylic acid has applications in pharmaceutical industry, particularly in the production of drugs and pharmaceutical intermediates.

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 144978-35-8 (S)-ethyl N-tert-butoxycarbonylpyroglutamate 
• 7149-65-7 ethyl (S)-pyroglutamate 
• 138423-86-6 Methyl (2S)-1-(tert-bytoxycarbonyl)-4,4-dimethylprolinate 
• 158392-74-6 O₁-tert-butyl O₂-methyl (2S)-4,4-dimethyl-5-oxopyrrolidine-1,2-dicarboxylate 
• 1001353-86-1 (S)-4,4-dimethylpyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester 2-ethyl ester 

Downstream Products

• 891183-50-9 4,4-dimethyl-L-proline 
• 1613055-95-0 C₂₀H₂₆BrNO₅ 
• 1613055-96-1 C₂₀H₂₆BrN₃O₂ 
• 1613055-97-2 C₂₆H₃₈BN₃O₄ 
• 1613055-98-3 C₃₂H₃₆F₃N₃O₅S 
• 1262400-68-9 (S)-4,4-Dimethyl-pyrrolidine-2-carboxylic acid methyl ester; hydrochloride 
• 212890-86-3 (S)-(-)-tert-butyl 2-(hydroxymethyl)-4,4-dimethylpyrrolidinecarboxylate 

Relevant articles and documents

As hepatitis c inhibitor spiro compound and its use in medicine

The invention provides a spiro compound serving as a hepatitis c inhibitor and application thereof in a medicine. The compound is a compound as shown in a formula (I) or a stereisomer, a geometric isomer, a tautomer, nitric oxide, an aquo-complex, a solvate, a metabolite, pharmaceutically acceptable salt or prodrug of the compound as shown in the formula (I). The invention also provides a pharmaceutical composition containing the compound, application of the compound and the pharmaceutical composition in inhibition of HCV (Hepatitis C Virus) copy and HCV virus protein, as well as the application of the compound and the pharmaceutical composition in prevention, handling, treatment or relieving of HCV infection or hepatitis c disease for a patient. The formula I is as shown in the specification.

HEPATITIS C VIRUS INHIBITORS

This disclosure concerns novel compounds of Formula (I) as defined in the specification and compositions comprising such novel compounds. These compounds are useful antiviral agents, especially in inhibiting the function of the NS5A protein encoded by Hepatitis C virus (HCV). Thus, the disclosure also concerns a method of treating HCV related diseases or conditions by use of these novel compounds or a composition comprising such novel compounds