10047-33-3

Basic information

• Product Name: Gastrin I Human
• Synonyms: PYROGLU-GLY-PRO-TRP-LEU-GLU-GLU-GLU-GLU-GLU-ALA-TYR-GLY-TRP-MET-ASP-PHE-NH2;PYR-GLY-PRO-TRP-LEU-GLU-GLU-GLU-GLU-GLU-ALA-TYR-GLY-TRP-MET-ASP-PHE-NH2;PYR-GLY-PRO-TRP-LEU-GLU-GLU-GLU-GLU-GLU-ALA-TYR-GLY-TRP-MET-ASP-PHE-NH2 AMMONIUM;PYR-GPWLEEEEEAYGWMDF-NH2;PGLU-GLY-PRO-TRP-LEU-GLU-GLU-GLU-GLU-GLU-ALA-TYR-GLY-TRP-MET-ASP-PHE-NH2;PGLU-GLY-PRO-TRP-LEU-GLU-GLU-GLU-GLU-GLU-ALA-TYR-GLY-TRP-MET-ASP-PHE-NH2 HUMAN;[18-PYROGLUTAMIC ACID]BIG GASTRIN I-(18-34)-PEPTIDE AMIDE, HUMAN;LITTLE GASTRIN I, HUMAN
• CAS NO: 10047-33-3
• Molecular Formula: C97H124N20O31S
• Molecular Weight: 2098.2
• EINECS: 233-157-0
• Product Categories: Peptide
• Mol File: 10047-33-3.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 2401.4±65.0 °C(Predicted)
• Appearance: /
• Density: 1.415±0.06 g/cm3(Predicted)
• Storage Temp.: −20°C
• PKA: 4.19±0.10(Predicted)
• CAS DataBase Reference: Gastrin I Human(CAS DataBase Reference)
• NIST Chemistry Reference: Gastrin I Human(10047-33-3)
• EPA Substance Registry System: Gastrin I Human(10047-33-3)

Safety Data

• Safety Statements: 22-24/25
• WGK Germany: 3
• F: 3-8-10-21
• Hazardous Substances Data: 10047-33-3(Hazardous Substances Data)

Usage

Description

Gastrin I Human, a linear peptide, is a gastrointestinal hormone produced by G cells in the stomach. It plays a crucial role in the regulation of gastric acid secretion and overall gastrointestinal function.

Uses

Used in Biochemical Research:
Gastrin I Human is used as a molecular weight marker for calibrating superdex 30 columns. This application is essential in ensuring accurate and reliable results in various biochemical research and analysis processes.
Used in Pharmaceutical Industry:
Gastrin I Human serves as a valuable compound in the pharmaceutical industry, where it can be utilized for the development of drugs targeting gastrointestinal disorders and conditions related to gastric acid secretion.
Used in Diagnostic Applications:
In the field of diagnostics, Gastrin I Human can be employed as a biomarker for the detection and monitoring of various gastrointestinal diseases, aiding in the early diagnosis and treatment of such conditions.
Used in Research and Development:
Gastrin I Human is also used in research and development for understanding the complex mechanisms of gastrointestinal function and the role of gastrin in regulating gastric acid secretion. This knowledge can contribute to the development of novel therapeutic strategies and treatments for related disorders.

Biochem/physiol Actions

Gastrin plays a major role in parietal cell function, gastric epithelial cell multiplication and differentiation. It acts as a modulator in maintaining and organizing gastric mucosa. It is produced in the stomach and stimulates gastric acid secretion.

InChI:InChI=1/C97H124N20O31S/c1-49(2)39-68(114-95(146)71(43-54-46-100-59-18-11-9-16-57(54)59)116-97(148)73-19-12-37-117(73)76(121)48-102-85(136)60-24-30-74(119)104-60)93(144)110-65(29-35-81(130)131)91(142)109-64(28-34-80(128)129)90(141)108-63(27-33-79(126)127)89(140)107-62(26-32-78(124)125)88(139)106-61(25-31-77(122)123)87(138)103-50(3)84(135)113-69(41-52-20-22-55(118)23-21-52)86(137)101-47-75(120)105-70(42-53-45-99-58-17-10-8-15-56(53)58)94(145)111-66(36-38-149-4)92(143)115-72(44-82(132)133)96(147)112-67(83(98)134)40-51-13-6-5-7-14-51/h5-11,13-18,20-23,45-46,49-50,60-73,99-100,118H,12,19,24-44,47-48H2,1-4H3,(H2,98,134)(H,101,137)(H,102,136)(H,103,138)(H,104,119)(H,105,120)(H,106,139)(H,107,140)(H,108,141)(H,109,142)(H,110,144)(H,111,145)(H,112,147)(H,113,135)(H,114,146)(H,115,143)(H,116,148)(H,122,123)(H,124,125)(H,126,127)(H,128,129)(H,130,131)(H,132,133)