101080-71-1Relevant articles and documents
Copper nanoparticle-doped silica cuprous sulfate as a highly efficient and reusable heterogeneous catalysis for N-arylation of nucleobases and N-heterocyclic compounds
Soltanirad, Mohammad Navid,Behrouz, Somayeh,Doroodmand, Mohammad Mahdi,Moghtaderi, Noushin
experimental part, p. 3915 - 3924 (2012/01/03)
A facile and simple protocol for Ullmann-type N-arylation of nucleobases with aryl halides is described using copper nanoparticle-doped silica cuprous sulfate (CN-DSCS) as a new and efficient heterogeneous catalysis. In this method, treatment of various n
Improved One-Step Procedure for the Preparation of 1-Substituted and 1,3-Disubstituted Uracils and 2-Thiouracils
Winckelmann, Ib,Larsen, Erik H.
, p. 1041 - 1044 (2007/10/02)
A convenient one-pot procedure for the synthesis of 1-substituted and 1,3-disubstituted uracils and 2-thiouracils consists of acylation of ureas or thioureas with methyl 3,3-dimethoxypropanoate in the presence of a strong base, and acidic work-up.The yields range from 36 to 99percent.In all cases, only one regioisomer is isolated.